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A luteal phase defect results in low production of the hormone progesterone, which is necessary for maintaining a pregnancy. IVF and related techniques (ICSI, ZIFT, GIFT) are called assisted reproductive technology (ART) techniques. In this case synthetic FSH by injection or Clomid (Clomiphene citrate) via a pill can be given to stimulate follicles to mature in the ovaries. This abnormality is usually surgically corrected in infancy. A variety of disorders ranging from hormonal disturbances to physical problems, to psychological problems can cause male infertility.  Although many treatment options are now available, in many cases treatment will not work.  In many instances, male infertility is caused by testicular damage resulting in an inability of the testicle to produce sperm.  Once damaged, the testicle will not usually regain its sperm-making capabilities; this aspect of male infertility is analogous to menopause (though not natural like menopause) for women and cannot usually be treated.  Despite medicine�s limited ability to treat male infertility, many successful treatment options are available for its many causes.  Besides testicular damage, the main causes of male infertility are low sperm production and poor sperm quality.   The Causes of Male Infertility Male infertility has many causes--from hormonal imbalances, to physical problems, to psychological and/or behavioral problems.  Moreover, fertility reflects a man�s �overall� health.  Men who live a healthy lifestyle are more likely to produce healthy sperm.  The following list highlights some lifestyle choices that negatively impact male fertility--it is not all-inclusive: · Smoking--significantly decreases both sperm count and sperm cell motility. · Prolonged use of marijuana and other recreational drugs. · Chronic alcohol abuse. · Anabolic steroid use--causes testicular shrinkage and infertility. · Overly intense exercise--produces high levels of adrenal steroid hormones which cause a    testosterone deficiency resulting in infertility. · Inadequate vitamin C and Zinc in the diet. · Tight underwear--increases scrotal temperature which results in decreased sperm production. · Exposure to environmental hazards and toxins such as pesticides, lead, paint, radiation, radioactive   substances, mercury,  benzene, boron, and heavy metals · Malnutrition and anemia. · Excessive stress! Women are advised not to use the drug for more than one day.

Smoking: Smoking significantly increases the risk of infertility in both men and women, and it may undermine the effects of fertility treatment. During emission, sperm are propelled forward by peristalsis. Reversal of Vasectomy and the Treatment of Male Infertility. (PDF, 4 MB) Urologic Clinics of North America, 1981. Birth after Preimplantation Diagnosis of the Cystic Fibrosis F508 Mutation by Polymerase Chain Reaction in Human Embryos Resulting from Intracytoplasmic Sperm Injection with Epididymal Sperm. (PDF, 2 MB) The Journal of the American Medical Association, 1994. In humans, infertility is the inability to become pregnant after one year of intercourse without contraception involving a male and female partner.[2] There are many causes of infertility, including some that medical intervention can treat.[3] Estimates from 1997 suggest that worldwide about five percent of all heterosexual couples have an unresolved problem with infertility. Evaluating the Infertile Male – Part 1. (PDF, 5 MB) Contemporary OB/GYN, 2004.

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Factors Affecting Fertility: Timing of Intercourse Intercourse prior to ovulation is key to maximizing the chance of pregnancy. In ZIFT, your doctor places the fertilized eggs -- at this stage called zygotes -- into your fallopian tubes within 24 hours. Women older than 35 years or couples with known risk factors for infertility may warrant evaluation at six months. The search included meta-analyses, randomized controlled trials, clinical trials, and systematic reviews. 41 Treatment of Unexplained Infertility Jump to section + Couples who have no identified cause of infertility should be counseled on timing of intercourse for the most fertile period (i.e., the six days preceding ovulation). Intracytoplasmic sperm injection (ICSI.)A single sperm is injected through a tiny needle into an egg.

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Treatment The cost of infertility treatment is high [34]. Assessment of efficacy of varicocele repair for male subfertility: a systematic review. Isolated FSH deficiency This is a very rare cause of infertility. 4 pmol/l for a low response and greater than or equal to 25.

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In most cases, surgery can be performed to either reverse these blockage or to retrieve sperm directly from the epididymis and testicles. Perspectives on infertility consultations in primary care: a qualitative study. Basic Work-up for Infertility It is very important to remember that infertility can occur as a result of one or more male or female factors. 17 Evaluation of male infertility starts with a history and physical examination focusing on previous fertility, pelvic or inguinal surgeries, systemic diseases, and exposures. Additionally, surgery, radiation or chemotherapy to treat tumors can affect male fertility. Diverse Spermatogenic Defects in Humans Caused by Y Chromosome Deletions Encompassing a Novel RNA-binding Protein Gene. (PDF, 7 MB) Nature Genetics, 1995. 18  If the semen analysis result is abnormal, further evaluation is indicated (Table 36–8,10,19,20).