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1 Infertility is medically defined as the inability to conceive after 12 months of unprotected sex. Showell MG, Brown J, Yazdani A, Stankiewicz MT, Hart RJ. Clinical Characterization of 42 Oligospermic or Azoospermic Men with Microdeletion of the AZFc Region of the Y Chromosome, and of 18 Children Conceived via ICSI. (PDF, 606 KB) Human Reproduction, 2002. Chlamydia test: Chlamydia can affect fertility, but antibiotics can treat it. Couples who do not conceive after treatment for six cycles with documented ovulation should also consider referral to an infertility specialist. Of azoospermic patients with Klinefelter syndrome, 20% show the presence of residual foci of spermatogenesis.

Chlamydia test: Chlamydia can affect fertility, but antibiotics can treat it. Lack of pregnancy Lack of pregnancy can be related to disruption of the cervical mucus, inadequate follicular development, presence of luteinized unruptured follicle syndrome, progesterone deficiency, and premature administration of hCG to trigger ovulation. Infrequent and light menstruation occurs in about 40% of women with ovulatory dysfunction. Causes of infertility include male factors, ovulatory dysfunction, uterine abnormalities, tubal obstruction, peritoneal factors, or cervical factors. The laparoscope aids diagnosis or therapeutic interventions with a few small cuts in the abdomen.[1] Laparoscopic surgery, also called minimally invasive surgery (MIS), bandaid surgery, or keyhole surgery, is a modern surgical technique. IUI is more commonly done when the man has a low sperm count, decreased sperm motility, or when infertility does not have an identifiable cause.

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Careful monitoring during treatment and pregnancy can help reduce the risk of complications. Generally, evaluation should be offered to couples who have not conceived after one year of unprotected vaginal intercourse. Antibodies against the sperm in the cervical mucus particularly often occur in sterile marriages.

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Thyroid problems: An overactive or underactive thyroid gland can lead to a hormonal imbalance. Patients have eunuchoidal body habitus, large testis, and a low ejaculatory volume. If the woman reaches the age of 40 during treatment, complete the current full cycle but do not offer further full cycles. In women aged 40–42 years who have not conceived after 2 years of regular unprotected intercourse or 12 cycles of artificial insemination (where 6 or more are by intrauterine insemination), offer 1 full cycle of IVF, with or without ICSI. Surgical treatment of myomas is indicated in cases of abnormal uterine bleeding, when the myoma is implicated in recurrent miscarriages or when it is thought to interfere with embryo implantation. With this treatment, the patient experience spermatogenesis, and therefore, it has the chance to have offspring if he wants to.

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Most of the time, basic semen analysis is all that's needed to diagnose male infertility. 29 When the semen analysis is abnormal, referral to a male fertility specialist or reproductive endocrinologist is warranted. Testicular histology reveals hyalinization of seminiferous tubules.[21] Some men with Klinefelter syndrome may be able to conceive with the help of assisted reproductive techniques. The types of ART include: In Vitro Fertilization (IVF) Gamete Intrafallopian Transfer (GIFT) Zygote Intrafallopian Transfer (ZIFT) Another ART procedure – Intracytoplasmic Sperm Injection (ICSI) – is used mainly in cases of male infertility to treat couples who cannot achieve fertilization due to the male partner’s extremely low number of normal, viable sperm. The AZFc Region of the Y Chromosome Features Massive Palindromes and Uniform Recurrent Deletions in Infertile Men. (PDF, 5 MB) Nature Genetics, 2001. Techniques for the Resolution of Testicular Obstruction. (PDF, 8 MB) Chapter 78 from textbook, Reconstructive Urology, 1992. Surgical Management of Male Infertility. (PDF, 2 MB) Chapter 12 from textbook, Male Infertility, 1992.