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Enzymatic Digestion of Testicular Tissue May Rescue the Intracytoplasmic Sperm Injection Cycle in Some Patients with Non-obstructive Azoospermia. (PDF, 66 KB) Human Reproduction, 1998. Hypogonadism Hypogonadism is an abnormally low level of testosterone, the male sex hormone involved in making sperm. Exposure to toxic agents can occur from occupational hazards or contaminated air, water, food supply or other exposures. These conditions, in which the body’s hormones are imbalanced, make conceiving more difficult.  Vaginal soreness and/or itchiness: Soreness or itchiness, especially in combination with discharge, could mean a vaginal infection. Anovulation can also cause cessation of periods (secondary amenorrhea) or excessive bleeding (dysfunctional uterine bleeding).

A decreased testosterone level with an increased FSH level points to primary hypogonadism. 47 Motivational interviewing techniques for modifiable risk factors, such as obesity, tobacco, illicit drugs, and alcohol, can decrease the targeted risk factor. National Collaborating Centre for Women's and Children's Health.

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In my case, the inability to conceive was the result of a condition called stage 4 endometriosis. The first transatlantic surgery (Lindbergh operation) ever performed was a laparoscopic gallbladder removal. Broekmans FJ, Kwee J, Hendriks DJ, Mol BW, Lambalk CB. The FAST study: fertility assessment and advice targeting lifestyle choices and behaviours: a pilot study.

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Varicocele A varicocele is a dilation of the veins of the pampiniform plexus of the scrotum. GIFT (gamete intrafallopian tube transfer) and ZIFT (zygote intrafallopian transfer).  Like IVF, these procedures involve retrieving an egg, combining it with sperm in a lab, and then transferring it back to your body. Ovarian Transplantation in a Series of Monozygotic Twins Discordant for Ovarian Failure. (PDF, 188 KB) The New England Journal of Medicine, 2007.

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In vitro fertilization (IVF). In this technique, your doctor places into your uterus that were fertilized in a dish. Other medical techniques are e.g. tuboplasty, assisted hatching, and preimplantation genetic diagnosis. Oocyte Vitrification – Women’s Emancipation Set in Stone. (PDF, 70 KB) Fertility and Sterility, 2008. The pituitary gland produces these hormones, so any problems with this gland may also influence infertility. Conventional In-vitro Fertilization vs Intracytoplasmic Sperm Injection for Patients Requiring Microsurgical Sperm Aspiration. (PDF, 3 MB) Human Reproduction, 1994. 8 However, if your doctor diagnoses you with infertility, then it’s likely that you’ll need some additional help to conceive.  This may be as simple as timing when you have sex, or you may need more advanced fertility treatment.   Discovering that you’re infertile can be overwhelming, but the right support can help you to conceive successfully. Additionally, because insulin-like growth factor (IGF) has been shown to have an effect on semen quality, its role in varicocele pathology has been studied.[25] One study showed that IGF levels significantly increased after a varicocelectomy to levels that were no different than fertile controls, suggesting that varicocele-related infertility may involve IGF.[26] Varicoceles lead to an increased incidence of sperm immaturity, apoptosis, and necrosis with severe disturbances in meiotic segregation compared to fertile men without varicoceles, and these parameters generally improve after repair.