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The fertilized egg is then implanted in the uterus. Semen and sperm Sometimes the sperm cannot travel effectively to meet the egg.

Patients are often short, with small firm testis and gynecomastia, but they have a normal-sized penis. There is a consistent association of Mycoplasma genitalium infection and female reproductive tract syndromes.

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In some cases, hormonal problems may be suspected if a man has abnormal hair growth, low libido, or other indications of sexual dysfunction. Nowadays, given the huge emotional impact caused by pregnancy loss, in those cases where two pregnancy losses have taken place, an analysis and treatment is advised. Affected individuals displayed more severe forms of infertility such as azoospermia and severe oligozoospermia.[27] Other causes[edit] Factors that can cause male as well as female infertility are: DNA damage DNA damage reduces fertility in female ovocytes, as caused by smoking,[28] other xenobiotic DNA damaging agents (such as radiation or chemotherapy)[29] or accumulation of the oxidative DNA damage 8-hydroxy-deoxyguanosine[30] DNA damage reduces fertility in male sperm, as caused by oxidative DNA damage,[31] smoking,[28] other xenobiotic DNA damaging agents (such as drugs or chemotherapy)[32] or other DNA damaging agents including reactive oxygen species, fever or high testicular temperature.[33] The damaged DNA related to infertility manifests itself by the increased susceptibility to denaturation inducible by heat or acid [34] or by the presence of double-strand breaks that can be detected by the TUNEL assay.[35] General factors Diabetes mellitus,[36][37] thyroid disorders,[38] undiagnosed and untreated coeliac disease,[39][40][41][42] adrenal disease[43] Hypothalamic-pituitary factors Hyperprolactinemia Hypopituitarism The presence of anti-thyroid antibodies is associated with an increased risk of unexplained subfertility with an odds ratio of 1. Ovary Transplantation for Fertility Preservation in Cancer Patients: Fresh and Frozen. (PDF, 1 MB) Chapter 42 from textbook Clinial Infertility, 2010. 8 Evaluation of Men Jump to section + Causes of male infertility include infection, injury, toxin exposures, anatomic variances, chromosomal abnormalities, systemic diseases, and sperm antibodies.

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48 However, there is no firm evidence that preconception counseling leads to increased live birth rates, in part because no studies on this topic have been performed. They should do so in the context of local and national priorities for funding and developing services, and in light of their duties to have due regard to the need to eliminate unlawful discrimination, to advance equality of opportunity and to reduce health inequalities. Intracytoplasmic Sperm Injection. (PDF, 4 MB) Chapter 47 from textbook Current Therapy in Equine Reproduction, 2006. Recent Advances in Male Reproductive Surgery. (PDF, 10 MB) Chapter 13 from Annual Progress in Reproductive Medicine, 1993.

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Y Chromosome Deletions in Azoospermic and Severely Oligozoospermic Men Undergoing Intracytoplasmic Sperm Injection after Testicular Sperm Extraction. (PDF, 336 KB) Human Reproduction, 1998. Many couples with infertility issues go on to have successful pregnancies. Enzymatic Digestion of Testicular Tissue May Rescue the Intracytoplasmic Sperm Injection Cycle in Some Patients with Non-obstructive Azoospermia. (PDF, 66 KB) Human Reproduction, 1998. 6,23 Anovulatory women should have further investigation to determine treatable causes such as thyroid disorders or hyperprolactinemia based on symptoms. Sperm motility Motility is described as the percent of sperm present with flagellar motion viewed on a bright-field or phase-contrast microscope. Conventional In-vitro Fertilization vs Intracytoplasmic Sperm Injection for Patients Requiring Microsurgical Sperm Aspiration. (PDF, 3 MB) Human Reproduction, 1994. Abundant Gene Conversion Between Arms of Palindromes in Human and Ape Y Chromosomes. (PDF, 340 KB)Nature, 2003. Primary infertility When a woman is unable to ever bear a child, either due to the inability to become pregnant or the inability to carry a pregnancy to a live birth she would be classified as having primary infertility. Traumatic Renal Hemorrhage Treatment by Arterial Embolization. (PDF, 3 MB) The Journal of Urology, 1973. Possible reasons for abnormal semen include: a lack of sperm – you may have a very low sperm count or no sperm at all sperm that aren't moving properly – this will make it harder for sperm to swim to the egg abnormal sperm – sperm can sometimes be an abnormal shape, making it harder for them to move and fertilise an egg Many cases of abnormal semen are unexplained. A combination of these factors leads to infertility 20 to 30 percent of the time. Vitrification of oocytes from endangered Mexican gray wolves (Canis lupus baileyi). (PDF, 319 KB) Theriogenology, 2010. Dr Barbieri of Harvard Medical School has indicated that cases of anovulation are quite frequent in women with a BMI (body mass index) over 27 kg/m2.[6][7][8] Unfortunately, not only does excess weight have a negative impact on ovulation itself,[9] but also on treatment efficacy and outcomes of ART (assisted reproductive technique).[10][11] Diagnosis[edit] Fertility awareness and LH measurement[edit] Symptoms-based methods of fertility awareness may be used to detect ovulation or to determine that cycles are anovulatory. He also developed a medical instrument company Wisap in Munich, Germany, which still produces various endoscopic instruments of high quality.