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Luttjeboer F, Harada T, Hughes E, Johnson N, Lilford R, Mol BW. Contents Definition[edit] "Demographers tend to define infertility as childlessness in a population of women of reproductive age," whereas "the epidemiological definition refers to "trying for" or "time to" a pregnancy, generally in a population of women exposed to" a probability of conception.[8] Currently, female fertility normally peaks at age 24 and diminishes after 30, with pregnancy occurring rarely after age 50.[9] A female is most fertile within 24 hours of ovulation.[9] Male fertility peaks usually at age 25 and declines after age 40.[9] The time needed to pass (during which the couple tries to conceive) for that couple to be diagnosed with infertility differs between different jurisdictions. 3) Insemination: Intrauterine insemination, also known as IUI, is a process by which sperm is washed and prepared for placement into the uterine cavity, therefore bypassing the cervix and bringing a higher concentration of motile sperm closer to the tubes and ovulated egg.

Clinical Characterization of 42 Oligospermic or Azoospermic Men with Microdeletion of the AZFc Region of the Y Chromosome, and of 18 Children Conceived via ICSI. (PDF, 606 KB) Human Reproduction, 2002. IVF and other fertility treatments have resulted in an increase in multiple births, provoking ethical analysis because of the link between multiple pregnancies, premature birth, and a host of health problems. Pro-life opposition to the destruction of embryos not transferred in vivo. Chronic conditions: These include AIDS or cancer.

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Refinements in the Methodology of Injection for Transvaginal Gamete Intra-Fallopian Transfer. (PDF, 2 MB) Human Reproduction, 1994. Epidemiological definition of infertility (for monitoring and surveillance) Women of reproductive age (15–49 years) at risk of becoming pregnant (not pregnant, sexually active, not using contraception and not lactating) who report trying unsuccessfully for a pregnancy for two years or more. (Reproductive Health Indicators) Infertility as a disability Disability: Infertility generates disability (an impairment of function), and thus access to health care falls under the Convention on the Rights of Persons with Disability.

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Primary vs. secondary infertility[edit] Primary infertility is defined as the absence of a live birth for women who desire a child and have been in a union for at least 12 months, during which they have not used any contraceptives.[14] The World Health Organisation also adds that 'women whose pregnancy spontaneously miscarries, or whose pregnancy results in a still born child, without ever having had a live birth would present with primarily infertility'.[15] Secondary infertility is defined as the absence of a live birth for women who desire a child and have been in a union for at least 12 months since their last live birth, during which they did not use any contraceptives.[15] Thus the distinguishing feature is whether or not the couple have ever had a pregnancy which led to a live birth. Several studies indicate that in some cases, a simple change in lifestyle could help patients suffering from anovulation. The Three-kidney Rat Model. (PDF, 2 MB) Investigative Urology, 1974. This combination of laboratory test results may indicate ovarian insufficiency or diminished ovarian reserve. Source : Preserving your fertility - University of Kansas Hospital PPT Presentation Summary : Preserving your fertility. Varicocele: Surgically removing a varicose vein in the scrotum may help.

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Adhesions with the surrounding tissue can develop as well, and reduce the motility of the tubes. However, medical treatment can be used to reduce the myoma size prior to removal. Testicular Transplantation and Autotransplantation. (PDF, 8 MB) Chapter 22 of textbook, Extracorporeal and Microvascular Surgery, 1982. Release of GnRH is stimulated by melatonin from the pineal gland and inhibited by testosterone, inhibin, corticotropin-releasing hormone, opiates, illness, and stress. These time intervals would seem to be reversed; this is an area where public policy trumps science. Reproductive Biology. (PDF, 147 KB) The Scientist, 1996. 6 Accuracy may be improved by use on midday or evening urine specimens, which correlate better with the peak in serum luteinizing hormone levels. However, it is widely acknowledged by doctors that it is usually very difficult for PCOS patients to lose weight. This abnormality is usually surgically corrected in infancy. Polycystic ovary syndrome (PCOS): The ovaries function abnormally and ovulation may not occur. Obesity Research from 2015 noted that many studies link obesity in men with infertility. Sperm or egg donation: If necessary, sperm or eggs can be received from a donor. Sperm can survive inside the female for up to 5 days, while an egg can be fertilized for up to 1 day after ovulation. LH mainly functions to stimulate testosterone secretion from the Leydig cells of the testicle, while FSH stimulates Sertoli cells to facilitate germ cell differentiation. Intracytoplasmic Sperm Injection. (PDF, 4 MB) Chapter 47 from textbook Current Therapy in Equine Reproduction, 2006. Once the follicular diameter reaches 18 mm and the E2 level is below 2000 pc/mL, ovulation is triggered by the administration of hCG (10,000 IU IM).