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ART: Gamete Intrafallopian Transfer (GIFT) GIFT is a procedure that involves ovarian stimulation, egg retrieval, and placing a mixture of sperm and eggs directly into the woman’s fallopian tube to foster fertilization inside the female body. Microsurgical Epididymal Sperm Aspiration and Assisted Reproductive Techniques. (PDF, 4 MB) Frontiers in Human Reproduction, 1991. A causal therapeutic approach does not exist and an important component is the prevention of hyperstimulation syndrome. Pregnancy After Testicular Transplant: Importance of Treating the Couple. (PDF, 5 MB) Fertility and Sterility, 1980. This should be followed by documentation of ovulation via serum progesterone.

Chromosomal defects Hereditary disorders, such as Klinefelter’s syndrome (when a male is born with two X chromosomes and one Y chromosome instead of one X and one Y) impacts the normal development of the male reproductive organs. Apparently there are only 0,014% of them (this could be an explanation of why they were not discovered until now). Laparoscopy: A thin, flexible tube with a camera at the end is inserted into the abdomen and pelvis, allowing a doctor to look at the fallopian tubes, uterus, and ovaries. Zygote Intrafallopian Transfer (ZIFT) Zygote Intrafallopian Transfer (ZIFT) is another variation of IVF.

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Several studies have demonstrated that an increase in BMI is correlated with a decrease in sperm concentration, a decrease in motility and an increase DNA damage in sperm. Studies show that the IUI is most successful when it is coupled with fertility drugs to enhance ovulation, with success rates between 5% and 20% per cycle. Further investigations may be requested according to the clinical presentation and the results of preliminary tests. Checking testosterone levels is advisable because an elevation above the reference range has a negative feedback effect on sperm production. Drugs, assisted reproductive technology, and surgery are common treatments.

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When one year of sexual relationships without birth control measures has not lead to a pregnancy. In many instances, sterility may be unexplained, but fertility treatments will be able to help. For example, polycystic ovarian syndrome is when the eggs only partially developed within the ovary and there is an excess of male hormones. Ultrasound: This may reveal issues such as ejaculatory duct obstruction or retrograde ejaculation. 34 Although intrauterine insemination has been shown to be equally effective as timed intercourse in unstimulated cycles, there is a modest increase in live birth rates when combined with ovarian stimulation. With this treatment, the patient experience spermatogenesis, and therefore, it has the chance to have offspring if he wants to.

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Grading is as follows: Grade 0 – No movement Grade 1 – Sluggish movement Grade 2 – Slow movement in a poorly defined direction Grade 3 – Slow or curved forward movement Grade 4 – Fast movement straight forward  Patients with abnormal sperm motility should be evaluated for the following: Pyospermia Antisperm antibodies Varicocele Sperm ultrastructural abnormalities Partial ductal obstruction Sperm morphology The head, acrosome, mid piece, and tail of individual spermatozoa are analyzed with phase-contrast microscopy after fixation with Papanicolaou stain. The patients often suffer from appearances of virilization and manlike hair patterns. Effect of metformin on ovulation and reproductive outcomes in women with polycystic ovary syndrome: a meta-analysis of randomized controlled trials. For those interested, we offer a free class entitled, “The Couple’s Guide to IVF”, that meets twice monthly and is open to the public. Laparoscopy is an operation performed in the abdomen or pelvis through small incisions, generally no more than a centimeter, with the assistance of a laparoscope attached to a camera which projects to a screen. Adding recombinant human FSH to HCG has been shown to be effective in achieving spermatogenesis in most patients.[18] Select patients with adult-onset idiopathic hypogonadotropic hypogonadism may respond to clomiphene citrate therapy.[19] Prader-Willi syndrome Patients have characteristic obesity, mental retardation, small hands and feet, and hypogonadotropic hypogonadism due to a GnRH deficiency. Environmental vs Genetic Sex Determination: A Possible Factor in Dinosaur Extinction? (PDF, 307 KB) Fertility and Sterility, 2004. Human chorionic gonadotropin (Ovidrel, Pregnyl): Used together with clomiphene, hMG, and FSH, this can stimulate the follicle to ovulate. This results in negative feedback stimulation of the hypothalamic-pituitary axis, causing an increase release of gonadotropins and testosterone. GIFT (gamete intrafallopian tube transfer) and ZIFT (zygote intrafallopian transfer).  Like IVF, these procedures involve retrieving an egg, combining it with sperm in a lab, and then transferring it back to your body. To assist in the luteal phase, the patient is given beta-HCG or progesterone. Vasectomy. (PDF, 5 MB) From the Encyclopedia of Reproduction, 1999. Large submucosal uterine fibroids may make the uterus' cavity bigger, increasing the distance the sperm has to travel.