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ICSI with Epididymal and Testicular Sperm Retrieval. (PDF, 1 MB) Male Sterility and Motility Disorders: Etiological Factors and Treatment, 1998. Abnormal semen may not be able to carry the sperm effectively. The treating doctor may feel inadequacy and the trust between the doctor and patient breaks down [43]. Nowadays, given the huge emotional impact caused by pregnancy loss, in those cases where two pregnancy losses have taken place, an analysis and treatment is advised.

Mannitol Induced Central Nervous System Toxicity in Renal Failure. (PDF, 4 MB) Investigative Urology, 1972. Compensatory and Obligatory Renal Growth in Rats. (PDF, 1 MB) American Journal of Physiology, 1974.

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They can interfere with implantation or block the fallopian tube, preventing sperm from fertilizing the egg. The Varicocele Dilemma. (PDF, 139 KB) Human Reproduction, 2001. Transplantation of Rat Kidneys with Acute Tubular Necrosis into Salt-loaded and Normal Recipients. (PDF, 2 MB)Surgery, 1975.

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Hormonal Problems A small percentage of male infertility is caused by hormonal problems.  The hypothalamus-pituitary endocrine system regulates the chain of hormonal events that enables testes to produce and effectively disseminate sperm.  Several things can go wrong with the hypothalamus-pituitary endocrine system: · The brain can fail to release gonadotrophic-releasing hormone (GnRH) properly.  GnRH stimulates   the hormonal pathway that causes testosterone synthesis and sperm production.  A disruption in   GnRH release leads to a lack of testosterone and a cessation in sperm production. · The pituitary can fail to produce enough lutenizing hormone (LH) and follicle stimulating hormone   (FSH) to stimulate the testes and testosterone/sperm production.  LH and FSH are intermediates   in the hormonal pathway responsible for testosterone and sperm production. · The testes� Leydig cells may not produce testosterone in response to LH stimulation. · A male may produce other hormones and chemical compounds which interfere with the   sex-hormone balance. This can help a man who cannot ejaculate normally, for example, because of a spinal cord injury. Do you have a family history of medical problems? Infertility and Impaired Fecundity in the United States, 1982-2010: Data from the National Survey of Family Growth.

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Combined causes of infertility and sterility A person can often have a subfertility issue that may be helped or made worse depending on their partner's circumstances. If you’re having trouble conceiving, you are certainly not alone. In some cases this can also cause considerable pain when breathing. Aetiology of Congenital Absence of Vas Deferens: Genetic Study of Three Generations. (PDF, 4 MB) Human Reproduction, 1993. First, ovarian stimulation takes place; therefore, the patient initially is pre-treated with GnRH-antagonists. Treatment of the cause: 26. Ovulation disorders: (Hyperprolactinaemic amenorrhoea) - Women with ovulatory disorders due to hyperprolactinaemia should be offered treatment with dopamine agonists such as bromocriptine. - Consideration should be given to safety for use in pregnancy and minimising cost when prescribing. This process bypasses the normal fertilization process, which may be compromised due to poor sperm function. Breeding with a proven fertile male must occur at the optimal time for the female. If a severe sperm defect is discovered, the testing on the female partner should be modified, and therapy can be immediately directed to the sperm problem. 8,46 Obesity impairs fertility and the response to fertility treatments, including in vitro fertilization; therefore, it is advisable to counsel patients who are obese to lose weight before conception or infertility treatments. Lack of pregnancy Lack of pregnancy can be related to disruption of the cervical mucus, inadequate follicular development, presence of luteinized unruptured follicle syndrome, progesterone deficiency, and premature administration of hCG to trigger ovulation.