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Factors contributing to the formation of antisperm antibodies in women are disturbance of normal immunoregulatory mechanisms, infection, violation of the integrity of the mucous membranes, rape and unprotected oral or anal sex. The man must be producing healthy sperm in quantities large enough to fertilize an egg cell. Medical conditions Some medical conditions can affect fertility. Women with regular menstrual cycles are likely to be ovulating and should be offered serum progesterone testing at day 21 to confirm ovulation.

Unexplained fertility affects about 10 percent of couples worldwide. Symptoms can also depend on what is causing the infertility. Start now with 1,000+ free video lectures given by award-winning educators!Global infertility guidelines: Strategy for development and dissemination Generating practice guidelines The revision and updating of the “WHO global Guidelines for infertility diagnosis, management and interventions for treatment” (1992) and the WHO manual for the investigation and diagnosis of the infertile couple” (1993) was initiated in January 2012.

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Classic Klinefelter syndrome has a 47, XXY karyotype and is caused by a nondisjunction during the first meiotic division, more commonly of maternal origin; mosaic forms are due to nondisjunction following fertilization. Assessment of efficacy of varicocele repair for male subfertility: a systematic review. Women with regular menstrual cycles are likely to be ovulating and should be offered serum progesterone testing at day 21 to confirm ovulation. ICSI with Epididymal and Testicular Sperm in Azoospermic Men. (PDF, 2 MB) From Treatment of Infertility: The New Frontiers, 1998. Sperm density Normal sperm density is greater than 20 million sperm/mL.

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Causes of Female Infertility The following causes may lead to infertility in women: Pelvic inflammatory disease, which can lead to blocked or damaged fallopian tubes. Post-ejaculatory urinalysis (urine testing), to check for retrograde ejaculation.

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Removal of polyps by the minimally invasive procedure hysteroscopy is associated with a doubling of pregnancy rate. This may partly be due to the fact that the average age at which women give birth to their first child also keeps rising because of occupational preferences and longer periods of education. That is why a continuous sonographic control and also lab-medical controls are made. Role of Semen Analysis in Subfertile Couples. (PDF, 250 KB) Fertility and Sterility, 2010. Endometriosis causes infertility by producing inflammation and scarring, which can result in not only pain but also potentially detrimental effects on egg, sperm or embryo. Ascites Petechial bleedings Weight loss Visual disorders Gait pattern in small steps 2. Ultrasound: This may reveal issues such as ejaculatory duct obstruction or retrograde ejaculation. Fertility Evaluation: General and Sexual History A detailed history includes: General history  This includes occupation and background, use of tobacco, alcohol and drugs, earlier diseases, history of abdominal surgery and earlier infections. Obesity and increased risk for oligozoospermia and azoospermia.