Infertility

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Causes include: Surgery: Pelvic surgery can sometimes cause scarring or damage to the fallopian tubes. Men with elevated prolactin levels present with gynecomastia, diminished libido, erectile dysfunction, and occasionally galactorrhea.

Some diseases: Conditions that are sometimes linked to lower fertility in males are anemia, Cushing's syndrome, diabetes, and thyroid disease. In GIFT, the sperm and eggs are mixed together before a doctor inserts them. WHO Manual for the Standardized Investigation and Diagnosis of the Infertile Couple.

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Pcos and Infertility Treatment Options

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As the rate of getting spontaneous pregnancy among infertile or subfertile couples is lower than that among normal fertile population, it is recommended to carry out the following diagnostic, evidence-based, work-up to detect any hidden treatable cause. The administration on GnRH should be extended throughout the luteal phase, or this should be supplemented with the administration of exogenous hCG. [202] Monitoring folliculogenesis is simpler than using hMG. Today, assisted reproductive techniques (ARTs) offer powerful new options. GIFT (gamete intrafallopian tube transfer) and ZIFT (zygote intrafallopian transfer).  Like IVF, these procedures involve retrieving an egg, combining it with sperm in a lab, and then transferring it back to your body. Obese women have a higher rate of recurrent, early miscarriage compared to non-obese women.

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Aromatase inhibitors are available for clinical use and FDA approved for treatment of postmenopausal breast cancer, but not for ovulation induction. A defect in any of these sperm structures may result in infertility that will not be detected by semen analysis.[60] Antisperm antibodies cause immune infertility.[23][24] Cystic fibrosis can lead to infertility in men. Fibrosis of the oviducts or uterine horns, probably a result of inflammation after infection or trauma, leads to infertility.

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The ovum has a much shorter life expectancy – less than 1 day if it is not fertilized. Primary sterility is the complete inability to become pregnant, while secondary sterility refers to the failure to conceive after a previous successful pregnancy. World Health Organization reference values for human semen characteristics. Causes of infertility include genetic abnormalities, certain acute and chronic diseases, exposure to certain environmental toxins, smoking, and excessive alcohol use (2). Another requirement for male fertility is a normal ductal system. 42 Urinary luteinizing hormone kits indicate the midcycle luteinizing hormone surge that precedes ovulation by one to two days. Povey AC, Clyma JA, McNamee R, et al.; Participating Centres of Chaps-UK. Medication. If you have ovulation problems, you may be prescribed drugs such as clomiphene citrate (Clomid, Serophene), gonadotropins (such as Gonal-F, Follistim, Humegon and Pregnyl), or letrozole. Possible problems could be that the egg is not released at the optimum time for fertilization, that it may not enter the fallopian tube, sperm may not be able to reach the egg, fertilization may fail to occur, transport of the zygote may be disturbed, or implantation fails. Basic Work-up for Infertility It is very important to remember that infertility can occur as a result of one or more male or female factors.


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Infertility Introduction
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