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For conception to take place, several events should happen correctly and at exactly the right time. In most cases, surgery can be performed to either reverse these blockage or to retrieve sperm directly from the epididymis and testicles.

5 percent of infertile men and may be controlled by medications like decongestants which contract the bladder sphincter or surgical reconstruction of the bladder neck can restore normal ejaculation. Y Chromosome Deletions in Azoospermic and Severely Oligozoospermic Men Undergoing Intracytoplasmic Sperm Injection after Testicular Sperm Extraction. (PDF, 336 KB) Human Reproduction, 1998. In addition, fertility treatments can be associated with health problems for women and resulting children (2), especially those related to the increased risk for multiple gestation. In patients with low gonadotropins and low estrogen, the treatment of choice is hMG, and the protocol is similar to that for patients with primary amenorrhea. Reversal of Vasectomy and the Treatment of Male Infertility. (PDF, 4 MB) Urologic Clinics of North America, 1981.

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For example, treatment for Hodgkin disease has been estimated to lead to infertility in as many as 80-100% of patients. Evaluation of cervical mucus is unreliable; therefore, investigation is not helpful with the management of infertility.

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A history and physical examination can help direct the evaluation. Cholesterol One study has found that high cholesterol levels may have an impact on fertility in women. This is caused by hormonal issues like thyroid hypo- or hyperfunction, hyperprolactinemia, or polycystic ovarian syndrome (PCOS) — all of which can lead to infertility.  Absence of periods: Temporary life stress or overexercising may cause you to occasionally skip a period. After repair, 40-70% of patients have improved semen parameters, while 40% are able to impregnate their partner without other interventions.

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There are other hormonal anomalies with no direct link to the ones mentioned above that can affect ovulation. Once the follicles (fluid filled sacs containing the eggs) reach a mature size, an HCG injection is administered which leads to final development and maturation of the eggs. Although relatively uncommon, eating disorders can negatively affect menstruation, fertility, and maternal and fetal well-being. Primary testicular causes of infertility Primary testicular problems may be chromosomal or nonchromosomal in nature. 17 Evaluation of male infertility starts with a history and physical examination focusing on previous fertility, pelvic or inguinal surgeries, systemic diseases, and exposures. Endometriosis (especially if chronic), uterine fibroids (myomas), or an abnormally-shaped uterus might interfere with conception as well.  Age  As women grow older, it usually becomes more challenging for them to conceive. The likelihood of fertilization improves significantly for men with low sperm concentrations.