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The AZFc Region of the Y Chromosome Features Massive Palindromes and Uniform Recurrent Deletions in Infertile Men. (PDF, 5 MB) Nature Genetics, 2001. 8 Couples with unexplained infertility may want to consider another year of intercourse before moving to more costly and invasive therapies, such as assisted reproductive technology. Endometriosis Endometriosis is when the tissue of the uterine lining grows outside of the uterus. Are Sequence Family Variants Useful for Identifying Deletions in the Human Y Chromosome? (PDF, 377 KB) The American Journal of Human Genetics, 2004.

Quantitative Analysis of Testicle Biopsy: Determination of Partial Obstruction and Prediction of Sperm Count after Surgery for Obstruction. (PDF, 4 MB) Fertility and Sterility, 1981. Myotonic dystrophy This is an autosomal dominant defect in the dystrophin gene that causes a delay in muscle relaxation after contraction. About one out of every three cases of infertility is due to the man alone, and we're somehow involved in infertility about half the time. For those interested, we offer a free class entitled, “The Couple’s Guide to IVF”, that meets twice monthly and is open to the public. Couples will have to consider the ethical and emotional aspects of this procedure.

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Gracia CR, Sammel MD, Coutifaris C, Guzick DS, Barnhart KT. Additionally, surgery, radiation or chemotherapy to treat tumors can affect male fertility. The Male-specific Region of the Human Y Chromsome is a Mosaic of Discrete Sequence Classes. (PDF, 754 KB) Nature, 2003.

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Men who are underweight tend to have lower sperm concentrations than those who are at a normal BMI. A review of records from other fertility doctors that you have seen is also important. This can reveal signs of endometriosis, scarring, blockages, and some irregularities of the uterus and fallopian tubes. In general, infertility is defined as the inability of couples to achieve pregnancy after ≥1 year of trying (1). The predictive value of hysterosalpingography for tubal and peritoneal infertility factors. Other conditions that affect the quality and quantity of sperm include: Primary testicular failure.

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High-cost treatments are out of financial reach for some couples. Cervical surgery can also sometimes cause scarring or shorten the neck of the womb (the cervix). It stimulates the ovaries to mature egg follicles. Microsurgery for Vasectomy Reversal and Vasoepididymostomy. (PDF, 13 MB) Urology, 1984. To prevent thromboembolism, a sufficient intake of fluids is necessary; also, ascites and pleural effusions should not lead to the wrong track and lead to a restriction of fluids. When anatomic variance or obstruction is suspected, referral for surgical evaluation and treatment is appropriate. Apparent Fertility of Human Spermatozoa from the Caput Epididymidis. (PDF, 4 MB) Journal of Andrology, 1989. Intracytoplasmic sperm injection is a process by which semen is washed and prepared for direct injection of one sperm into each egg collected during the IVF process. An ultrasonography unit and an endocrine laboratory capable of performing daily determinations of E2, FSH, and LH are necessary. [186, 187, 188, 189] Multiple adverse effects and complications may occur during the use of the gonadotropins, including (1) multiple pregnancy (24-33%), (2) ectopic pregnancy (5-8%), (3) miscarriages (15-21%), (4) ovarian torsion and rupture, and (5) ovarian hyperstimulation syndrome, which is the most severe. [190, 191] Whittemore et al, using a large combined data set derived from case-controlled studies in the United States, showed that the increase of ovarian cancer associated with infertility might be due to the use of fertility drugs. [192] Ovarian hyperstimulation syndrome is an iatrogenic condition that occurs in patients undergoing ovulation induction with hMG or controlled ovarian hyperstimulation (COH) for assisted reproductive technologies. Not PPT Presentation Summary : Infertility Statistics. Semen and sperm Sometimes the sperm cannot travel effectively to meet the egg.