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Radiation therapy While Leydig cells are relatively radioresistant because of their low rate of cell division, the Sertoli and germ cells are extremely radiosensitive. Medications, treatments, and drugs Some drugs can affect fertility in a woman. Retrograde Ejaculation: Is a condition in which semen is ejaculated into the bladder rather than out through the urethra because the bladder sphincter does not close during ejaculation.  If this disorder is present, ejaculate volume is small and urine may be cloudy after ejaculation.  This condition affects 1.

Common causes of infertility of females include: ovulation problems (e.g. polycystic ovarian syndrome, PCOS, the leading reason why women present to fertility clinics due to anovulatory infertility.[58]) tubal blockage pelvic inflammatory disease caused by infections like tuberculosis age-related factors uterine problems previous tubal ligation endometriosis advanced maternal age immune infertility Males[edit] The main cause of male infertility is low semen quality. Your doctor may suggest that you take gonadotropin if you have unexplained infertility or when other kinds of treatment haven't helped you get pregnant. Healthcare providers may also conduct a semen analysis to check the number, shape, and movement of sperm.

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Ovulation disorders appear to be the most common cause of infertility in women. If the epididymis is blocked, sperm may not be ejaculated properly. There is no reliable means to predict whether the use of any treatment option will be successful and after how many attempts.

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Luttjeboer F, Harada T, Hughes E, Johnson N, Lilford R, Mol BW. Abdominal myomectomy is a surgical procedure performed through a very low horizontal abdominal incision allowing access to the uterus for removal of fibroids.

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Many more couples, however, experience involuntary childlessness for at least one year: estimates range from 12% to 28%.[4] Male infertility is responsible for 20–30% of infertility cases, while 20–35% are due to female infertility, and 25–40% are due to combined problems in both parts.[2][5] In 10–20% of cases, no cause is found.[5] The most common cause of female infertility is ovulatory problems, which generally manifest themselves by sparse or absent menstrual periods.[6] Male infertility is most commonly due to deficiencies in the semen, and semen quality is used as a surrogate measure of male fecundity.[7] Women who are fertile experience a natural period of fertility before and during ovulation, and they are naturally infertile for the rest of the menstrual cycle. Tubal occlusion A tubal occlusion means there is a blockage in the fallopian tube. Submucosal fibroids are the type if fibroid that has clearly been demonstrated to reduce pregnancy rate, roughly by 50%, and removal of which will double pregnancy rate. The later they are detected, the more complicated having children becomes. The patient's electrolyte levels must be checked to consider the need for diuretics. Pregnancy after Vasovasostomy for Vasectomy Reversal: A Study of Factors Followed for 10 Years. (PDF, 3 MB)Human Reproduction, 1989. Graft-versus-host Reactivity and Renal Allograft Survival in Rats Given Allogeneic Spleen Cells or Spleen Allografts.(PDF, 2 MB) Transplantation, 1976. Quantitative Analysis of Testicle Biopsy: Determination of Partial Obstruction and Prediction of Sperm Count after Surgery for Obstruction. (PDF, 4 MB) Fertility and Sterility, 1981. Primary infertility is when a couple has not conceived after trying for at least 12 months without using birth control Secondary infertility is when they have previously conceived but are no longer able to. With laparoscopy providing tissue diagnosis, and helping to achieve the final diagnosis without any significant complication and less operative time, it can be safely concluded that diagnostic laparoscopy is a safe, quick, and effective adjunct to non‑surgical diagnostic modalities, for establishing a conclusive diagnosis, but whether it will replace imaging studies as a primary modality for diagnosis needs more evidence.[34] History[edit] Hans Christian Jacobaeus It is difficult to credit one individual with the pioneering of the laparoscopic approach. The Disappearing Y Chromosome – “I Told You So!” (PDF, 266 KB) Human Reproduction, 1997. Chances of conception People who are concerned about their fertility should be informed that over 80% of couples in the general population will conceive within 1 year if: - the woman is aged under 40 years - they do not use contraception and have regular sexual intercourse. Half of those who do not conceive in the first year will do so in the second year (cumulative pregnancy rate over 90%)(cumulative pregnancy rate over 90%) 5. Medical conditions Some medical conditions can affect fertility. Undescended testicles During fetal development one or both testicles may fail to descend from the abdomen into the sac that normally contains the testicles. Your doctor may ask you many of the following questions: How long have you been trying to get pregnant? Common causes of infertility of females include: ovulation problems (e.g. polycystic ovarian syndrome, PCOS, the leading reason why women present to fertility clinics due to anovulatory infertility.[58]) tubal blockage pelvic inflammatory disease caused by infections like tuberculosis age-related factors uterine problems previous tubal ligation endometriosis advanced maternal age immune infertility Males[edit] The main cause of male infertility is low semen quality.