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As treatment begins, couples may experience cycles of optimism and despair with each passing menstrual cycle. Mutations in the Cystic Fibrosis Gene in Patients with Congenital Absence of the Vas Deferens. (PDF, 5 MB) New England Journal of Medicine, 1995. Adverse effects of metformin include GI intolerance, nausea, vomiting, and abdominal cramps. Ovarian Transplantation between Monozygotic Twins Discordant for Premature Ovarian Failure. (PDF, 315 KB) The New England Journal of Medicine, 2005.

Apparently there are only 0,014% of them (this could be an explanation of why they were not discovered until now). 389 KB ARTICLES FROM THE 1980s Microsurgical Reversal of Female Sterilization: The Role of Tubal Length. (PDF, 2 MB) Fertility and Sterility, 1980. Sperm can survive inside the female for up to 5 days, while an egg can be fertilized for up to 1 day after ovulation.

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Torsion: Is a common problem affecting fertility that is caused by a supportive tissue abnormality which allows the testes to twist inside the scrotum which is characterized by extreme swelling.  Torsion pinches the blood vessels that feed the testes shut which causes testicular damage.  If emergency surgery is not performed to untwist the testes, torsion can seriously impair fertility and cause permanent infertility if both testes twist. Refinements in the Methodology of Injection for Transvaginal Gamete Intra-Fallopian Transfer. (PDF, 2 MB) Human Reproduction, 1994. In some cases, hormonal problems may be suspected if a man has abnormal hair growth, low libido, or other indications of sexual dysfunction. This process has revolutionized assisted reproductive technology and the way reproductive endocrinologists can help people in having a baby.

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In many cases, there are tests that can help find the cause(s) of male infertility. If stem cells remain viable after radiation therapy, patients may regain fertility within several years. Birth after Preimplantation Diagnosis of the Cystic Fibrosis F508 Mutation by Polymerase Chain Reaction in Human Embryos Resulting from Intracytoplasmic Sperm Injection with Epididymal Sperm. (PDF, 2 MB) The Journal of the American Medical Association, 1994.

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The menopause is premature when it occurs before 40 years of age. The use of Epididymal and Testicular Spermatozoa for Intracytoplasmic Sperm Injection: The Genetic Implications for Male Infertility. (PDF, 8 MB) Human Reproduction, 1995. Evaluation of the Female Partner: Evidence of Ovulation (Continued) Progesterone test. In addition to stimulation by FSH, Sertoli cell function is modulated by intratesticular testosterone and signals from peritubular myoid cells. Human menopausal gonadotropins Crowe discovered that the gonads were under the control of the anterior hypophysis. [175] Zondek and Aschheim discovered that FSH and LH were responsible for the development of the gonads in immature animals and confirmed Crowe's work. [135, 136] In the 1930s, ovulation induction was attempted by using gonadotropins from a mare, but its use was discontinued because of the development of antibodies. [176, 177] Borth et al demonstrated the effect of FSH and LH extracted from menopausal urine. [178, 179] Gemzell reported the first ovulation induction using human pituitary gonadotropin in 1958, and the first pregnancy was reported in 1960. [180, 181] Lunenfeld reported preliminary results using hMG; however, in 1963, it was definitely established as a real ovulation induction agent. [182, 183, 184] Human menopausal gonadotropin (hMG [eg, Repronex, Menopur]) contains 75 U of FSH and 75 U of LH per mL, although the concentration may vary among batches (ranges from FSH at 60-90 U and LH at 60-120 U). Ovarian Transplantation between Monozygotic Twins Discordant for Premature Ovarian Failure. (PDF, 315 KB) The New England Journal of Medicine, 2005. Congenital Absence of the Vas Deferens: The Fertilizing Capacity of Human Epididymal Sperm. (PDF, 3 MB) New England Journal of Medicine, 1990. In patients with obstructive azoospermia and normal gonadotropin levels, sperm can be obtained through microsurgical epididymal sperm aspiration or testicular biopsy. [213] Fertilization of the oocytes is performed using IVF/intracytoplasmic sperm injection. Contents Signs and symptoms[edit] Anovulation is usually associated with specific symptoms. Surgical procedures for women If the fallopian tubes are blocked or scarred, surgical repair may make it easier for eggs to pass through.