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Sulfasalazine: This anti-inflammatory drug can significantly lower a man's sperm count. IVF in action Intracytoplasmic sperm injection (ICSI): A single sperm is injected into an egg to achieve fertilization during an IVF procedure. Evaluation may be initiated sooner in patients who have risk factors for infertility or if the female partner is older than 35 years.

IVF and other fertility treatments have resulted in an increase in multiple births, provoking ethical analysis because of the link between multiple pregnancies, premature birth, and a host of health problems. Judaism and Reproductive Technology. (PDF, 2 MB) 2010.

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Varicocele A varicocele is a swelling of the veins that drain the testicle, which can impact sperm quality. Ovulation should be documented by serum progesterone level measurement at cycle day 21. To Transplant or Not to Transplant – That Is the Question. (PDF, 3 MB) 2010. Intercourse 2 or 3 times per week may be considered average, although the frequency varies. A mouse study has suggested that ingredients in some household detergents may reduce fertility.

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In such cases, OPKs and those fertility monitors which are based on LH may show false results, with an increased number of false positives or false negatives. American Urological Association Education and Research, Inc. London, United Kingdom: National Institute for Health and Clinical Excellence (NICE); February 2013:1–63. (Clinical guideline no. Adding recombinant human FSH to HCG has been shown to be effective in achieving spermatogenesis in most patients.[18] Select patients with adult-onset idiopathic hypogonadotropic hypogonadism may respond to clomiphene citrate therapy.[19] Prader-Willi syndrome Patients have characteristic obesity, mental retardation, small hands and feet, and hypogonadotropic hypogonadism due to a GnRH deficiency. Testicular histology reveals hyalinization of seminiferous tubules.[21] Some men with Klinefelter syndrome may be able to conceive with the help of assisted reproductive techniques. Exposure to some chemicals: Some pesticides, herbicides, metals, such as lead, and solvents have been linked to fertility problems in both men and women.

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In this treatment, millions of healthy sperm are injected into the woman’s uterus at the time of ovulation.  IVF: The most effective assisted reproductive treatment is in vitro fertilization or IVF. A typical disease is polycystic ovarian syndrome. Infertility tests for women A woman will undergo a general physical examination, and the doctor will ask about her medical history, medications, menstruation cycle, and sexual habits. A sperm count of under 15 million is considered low. Affected individuals displayed more severe forms of infertility such as azoospermia and severe oligozoospermia.[27] Other causes[edit] Factors that can cause male as well as female infertility are: DNA damage DNA damage reduces fertility in female ovocytes, as caused by smoking,[28] other xenobiotic DNA damaging agents (such as radiation or chemotherapy)[29] or accumulation of the oxidative DNA damage 8-hydroxy-deoxyguanosine[30] DNA damage reduces fertility in male sperm, as caused by oxidative DNA damage,[31] smoking,[28] other xenobiotic DNA damaging agents (such as drugs or chemotherapy)[32] or other DNA damaging agents including reactive oxygen species, fever or high testicular temperature.[33] The damaged DNA related to infertility manifests itself by the increased susceptibility to denaturation inducible by heat or acid [34] or by the presence of double-strand breaks that can be detected by the TUNEL assay.[35] General factors Diabetes mellitus,[36][37] thyroid disorders,[38] undiagnosed and untreated coeliac disease,[39][40][41][42] adrenal disease[43] Hypothalamic-pituitary factors Hyperprolactinemia Hypopituitarism The presence of anti-thyroid antibodies is associated with an increased risk of unexplained subfertility with an odds ratio of 1. Some diseases: Conditions that are sometimes linked to lower fertility in males are anemia, Cushing's syndrome, diabetes, and thyroid disease. The effects of age on fertility are moderate and do not begin to take an effect until the late 30s.