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The sperm can either be mixed with the eggs to allow normal fertilization (conventional insemination) or by injecting one sperm into each mature egg (ICSI). Other medical techniques are e.g. tuboplasty, assisted hatching, and preimplantation genetic diagnosis. Additionally, because insulin-like growth factor (IGF) has been shown to have an effect on semen quality, its role in varicocele pathology has been studied.[25] One study showed that IGF levels significantly increased after a varicocelectomy to levels that were no different than fertile controls, suggesting that varicocele-related infertility may involve IGF.[26] Varicoceles lead to an increased incidence of sperm immaturity, apoptosis, and necrosis with severe disturbances in meiotic segregation compared to fertile men without varicoceles, and these parameters generally improve after repair. Klinefelter�s Syndrome: Is a genetic condition in which each cell in the human body has an additional X chromosome--men with Klinefelter�s Syndrome have one Y and two X chromosomes.  Physical symptoms include peanut-sized testicles and enlarged breasts.  A chromosome analysis is used to confirm this analysis.  If this condition is treated in its early stages (with the drug hCG), sperm production may commence and/or improve.  However, Klinefelter�s Syndrome eventually causes all active testicular structures to atrophy.  Once testicular failure has occurred, improving fertility is impossible. Outcome of Intracytoplasmic Sperm Injection with Testicular Spermatozoa in Obstructive and Non-obstructive Azoospermia. (PDF, 426 KB) Human Reproduction, 1996.

A smaller amount may suggest a structural or hormonal problem leading to deficient semen production; 2) sperm concentration – normal concentration should be at least 20 million sperm per 1 ml of semen. Women older than 35 years or couples with known risk factors for infertility may warrant evaluation at six months. Smoking: Smoking significantly increases the risk of infertility in both men and women, and it may undermine the effects of fertility treatment. A typical adverse effect can be ovarian hyperstimulation. 389 KB ARTICLES FROM THE 1980s Microsurgical Reversal of Female Sterilization: The Role of Tubal Length. (PDF, 2 MB) Fertility and Sterility, 1980. Cervical surgery can sometimes cause scarring or shortening of the cervix.

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Ideally, the cause of the infertility is reversible and then conception can result from natural sex. The sperm can either be mixed with the eggs to allow normal fertilization (conventional insemination) or by injecting one sperm into each mature egg (ICSI). CASA measures the following parameters: Curvilinear velocity – The average distance per unit time between successive sperm positions) Straight-line velocity – The speed of forward direction Linearity – The straight-line velocity divided by the curvilinear velocity In addition, the program measures the average path velocity, the amplitude of lateral head displacement, and the flagellar beat frequency, and it is used to evaluate for evidence of hyperactivation.

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The gonadotropins in these formulations are FSH, and in some cases, a combination of FSH and LH (luteinizing hormone). Ovulation induction in polycystic ovary syndrome [published corrections appear in J Obstet Gynaecol Can. Luciano AA, Peluso J, Koch EI, Maier D, Kuslis S, Davison E. However, about one in five cases of infertility has no clear diagnosed cause.[73] In Britain, male factor infertility accounts for 25% of infertile couples, while 25% remain unexplained. Key to the diagnosis of male infertility is a semen analysis, which assesses primarily sperm numbers, sperm movement and sperm form.

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Reduced fecundability in women with prenatal exposure to cigarette smoking. The World Health Organization (WHO) published reference ranges for semen testing in 2010. [45] These include “lower reference limits” representing the 5th percentiles for semen characteristics. [46] Note that the lower reference limits do not serve as a cut-point between “fertile” and “infertile.” Volume Normal ejaculate volume is 1. However, if the cycle lasts from 21 to 35 days, it’s still considered normal, as long it is consistent. On the contrary to women, in which is the issue can more commonly be detected, most male fertility issues, other than those caused by infections, are unexplained.