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Unexpected resilience of species with temperature-dependent sex determination at the Cretaceous–Palaeogene boundary. (PDF, 238 KB) Biology Letters, 2010. Both pituitary insufficiency and pituitary excess cause infertility.

It was broken down into male and female categories. Women with obesity have a lower probability of conceiving and are at a higher risk for issues during pregnancy than those without weight issues. Partners may become more anxious to conceive, increasing sexual dysfunction.[17] Marital discord often develops, especially when they are under pressure to make medical decisions. It has been suggested that infertility be classified as a form of disability.[22] Causes[edit] Immune infertility[edit] Antisperm antibodies (ASA) have been considered as infertility cause in around 10–30% of infertile couples.[23] In both men and women, ASA production are directed against surface antigens on sperm, which can interfere with sperm motility and transport through the female reproductive tract, inhibiting capacitation and acrosome reaction, impaired fertilization, influence on the implantation process, and impaired growth and development of the embryo. Obese women have a higher rate of recurrent, early miscarriage compared to non-obese women. In addition to a careful history, a physical evaluation may also be performed.

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Microscopic Vasoepididymostomy: Specific Microanastomosis to the Epididymal Tubule. (PDF, 15 MB) Fertility and Sterility, 1978. When it is possible to find the cause, treatments may include medicines, surgery, or assisted reproductive technology. Risk factors for the formation of antisperm antibodies in men include the breakdown of the blood‑testis barrier, trauma and surgery, orchitis, varicocele, infections, prostatitis, testicular cancer, failure of immunosuppression and unprotected receptive anal or oral sex with men.[23][24] Sexually transmitted infections[edit] Infections with the following sexually transmitted pathogens have a negative effect on fertility: Chlamydia trachomatis and Neisseria gonorrhoeae. Microsurgery for the Undescended Testicle. (PDF, 5 MB) Urologic Clinics of North America, 1982.

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Of azoospermic patients with Klinefelter syndrome, 20% show the presence of residual foci of spermatogenesis. Immunological testing has not been proven to have any value in infertility patients without a history of 2 or more miscarriages.

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The Effect of Female Age and Ovarian Reserve on Pregnancy Rate in Male Infertility: Treatment of Azoospermia with Sperm Retrieval and Intracytoplasmic Sperm Injection. (PDF, 66 KB) Human Reproduction, 1997. Of particular relevance amongst diseases affecting the testes are testicular infection or orchitis. Most typical are decreased libido, erectile dysfunction, orgasmic dysfunction, and ejaculatory dysfunction. Investigations will be requested to prove the clinical diagnosis and to exclude other close possibilities. Hypothalamic-pituitary-gonadal axis stimulatory and inhibitory signals. The effect of age upon men's fertility is less clear.[citation needed] In people going forward for IVF in the UK, roughly half of fertility problems with a diagnosed cause are due to problems with the man, and about half due to problems with the woman. He also developed a medical instrument company Wisap in Munich, Germany, which still produces various endoscopic instruments of high quality. In this condition, semen ejaculates backwards into the bladder instead of out the penis.