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World Health Organization reference values for human semen characteristics. A doctor or WHNP takes a medical history and gives a physical examination. Bhaskar Dutta/Photoshare Clinical definitions Infertility is “a disease of the reproductive system defined by the failure to achieve a clinical pregnancy after 12 months or more of regular unprotected sexual intercourse.”… (WHO-ICMART glossary1). “Infertility is the inability of a sexually active, non-contracepting couple to achieve pregnancy in one year.

Factors contributing to the formation of antisperm antibodies in women are disturbance of normal immunoregulatory mechanisms, infection, violation of the integrity of the mucous membranes, rape and unprotected oral or anal sex. Cystic fibrosis: This is a chronic disease that results in the creation of a sticky mucus. Stem cell therapy[edit] Nowadays, there are several treatments (still in experimentation) related with stem cell therapy. The chance of a multiple birth is lower with an oral fertility drug. The four types of third party reproduction are 1) sperm donation – a process by which donated sperm is used for insemination in the uterus, or for fertilization of eggs in the IVF process; 2) egg or ovum donation – a process by which an egg donor undergoes an IVF cycle in order to obtain her eggs which are then donated and fertilized.

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Screening tests include increased plasma 17-hydroxylase and urine 17-ketosteroids. LH mainly functions to stimulate testosterone secretion from the Leydig cells of the testicle, while FSH stimulates Sertoli cells to facilitate germ cell differentiation.

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Treatment of tubal obstruction generally requires referral for subspecialty care. Cervical surgery can sometimes cause scarring or shortening of the cervix. Partners may become more anxious to conceive, increasing sexual dysfunction.[17] Marital discord often develops, especially when they are under pressure to make medical decisions.

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Affected individuals displayed more severe forms of infertility such as azoospermia and severe oligozoospermia.[27] Other causes[edit] Factors that can cause male as well as female infertility are: DNA damage DNA damage reduces fertility in female ovocytes, as caused by smoking,[28] other xenobiotic DNA damaging agents (such as radiation or chemotherapy)[29] or accumulation of the oxidative DNA damage 8-hydroxy-deoxyguanosine[30] DNA damage reduces fertility in male sperm, as caused by oxidative DNA damage,[31] smoking,[28] other xenobiotic DNA damaging agents (such as drugs or chemotherapy)[32] or other DNA damaging agents including reactive oxygen species, fever or high testicular temperature.[33] The damaged DNA related to infertility manifests itself by the increased susceptibility to denaturation inducible by heat or acid [34] or by the presence of double-strand breaks that can be detected by the TUNEL assay.[35] General factors Diabetes mellitus,[36][37] thyroid disorders,[38] undiagnosed and untreated coeliac disease,[39][40][41][42] adrenal disease[43] Hypothalamic-pituitary factors Hyperprolactinemia Hypopituitarism The presence of anti-thyroid antibodies is associated with an increased risk of unexplained subfertility with an odds ratio of 1. Fertility Evaluation: General and Gynecological Examination For women, a visual evaluation of hair distribution and of body and breast development can indicate endocrinopathy or various development deficiencies. Instructions for collecting the sample should include abstinence from ejaculation for 48 to 72 hours. Patients present with oligospermia but have LH levels within the reference range. The virus may either directly damage the seminiferous tubules or indirectly cause ischemic damage as the intense swelling leads to compression against the tough tunica albuginea. If the epididymis is blocked, sperm may not be ejaculated properly. If conception does not occur after many months or years of trying, it can lead to stress and possibly depression. Although sperm quality deteriorates as men age, this does not create a problem until after the age of 60.