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An estimated 28% of all couples seeking reproductive assistance may have normal findings on their clinical evaluation, making the unexplained infertility a more common provisional diagnosis. Medical treatments[edit] Medical treatment of infertility generally involves the use of fertility medication, medical device, surgery, or a combination of the following. Hofherr SE, Wiktor AE, Kipp BR, Dawson DB, Van Dyke DL. Aromatase inhibitors are available for clinical use and FDA approved for treatment of postmenopausal breast cancer, but not for ovulation induction. Another requirement for male fertility is a normal ductal system. Outside pregnancy and lactation, women with high levels of prolactin may have irregular ovulation cycles and fertility problems.

About 10% to 15% of couples will not be able to achieve pregnancy after one year of unprotected intercourse. Non-steroidal anti-inflammatory drugs (NSAIDs): Long-term use of aspirin or ibuprofen may make it harder to conceive. Full history taking of both partners usually denotes the underlying problem [17-23], (Appendix 1).

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Normal Intrauterine Pregnancy After Reversal of Tubal Sterilization in the Wife and Vasectomy in the Husband.(PDF, 1 MB) Fertility and Sterility, 1978. Intracytoplasmatic Sperm Injection (ICSI) An intracytoplasmatic sperm injection is also a form of artificial insemination.

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Broekmans FJ, Kwee J, Hendriks DJ, Mol BW, Lambalk CB. Conventional In-vitro Fertilization vs Intracytoplasmic Sperm Injection for Patients Requiring Microsurgical Sperm Aspiration. (PDF, 3 MB) Human Reproduction, 1994.

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Environmental vs Genetic Sex Determination: A Possible Factor in Dinosaur Extinction? (PDF, 307 KB) Fertility and Sterility, 2004. For example, polycystic ovarian syndrome is when the eggs only partially developed within the ovary and there is an excess of male hormones. This indicates whether the fallopian tubes are open or blocked. Surgical sperm aspiration: The sperm is removed from part of the male reproductive tract, such as the vas deferens, testicle, or epididymis. Mannitol Induced Central Nervous System Toxicity in Renal Failure. (PDF, 4 MB) Investigative Urology, 1972. Round Spermatid Injection. (PDF, 422 KB) Fertility and Sterility, 2000. Group II: hypothalamic-pituitary-ovarian dysfunction (predominately polycystic ovary syndrome). This mucus mainly affects the lungs, but males may also have a missing or obstructed vas deferens. 6,28 Additionally, postcoital testing of cervical mucus is no longer recommended because it does not affect clinical management or predict the inability to conceive. VITRIKAS, MD, David Grant Medical Center Family Medicine Residency, Travis Air Force Base, California Am Fam Physician. 2015 Mar 1;91(5):308-314.   Patient information: See related handout on infertility, written by the authors of this article.   Related letter: Natural Procreative Technology for Treating Infertility This clinical content conforms to AAFP criteria for continuing medical education (CME). About a third of the time, infertility can be traced to the woman. These assistance systems meet the demands of true solo surgery assistance systems and are robust, versatile, and easy to use. 40 Patients using these agents should be counseled about these risks.