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This should be followed by documentation of ovulation via serum progesterone. Its use is controversial in patients with a history of breast cancer. Chemotherapy: Some types may significantly reduce sperm count. Therefore, this problem must be corrected first or concomitantly to obtain an ovulatory response. In general, infertility is defined as the inability of couples to achieve pregnancy after ≥1 year of trying (1).

Patients with hyperthyroidism or hypothyroidism must be treated accordingly. [210, 211] Weight reduction should be part of the treatment because it helps the patient's response to ovulation induction. [212] Treatment of Male Factors Asthenospermia associated with varicocele is treated surgically with varicocelectomy or with embolization of the spermatic veins. 6,23 Anovulatory women should have further investigation to determine treatable causes such as thyroid disorders or hyperprolactinemia based on symptoms. The Disappearing Y Chromosome – “I Told You So!” (PDF, 266 KB) Human Reproduction, 1997.

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However, some have suggested that patients should avoid conception for 6 months to 2 years after completion of radiation therapy because of the possibility of chromosomal aberrations in their sperm caused by the mutagenic properties of radiation therapy. The physician or WHNP may also suggest using a conception cap cervical cap, which the patient uses at home by placing the sperm inside the cap and putting the conception device on the cervix, or intrauterine insemination (IUI), in which the doctor or WHNP introduces sperm into the uterus during ovulation, via a catheter.

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The Effect of Female Age and Ovarian Reserve on Pregnancy Rate in Male Infertility: Treatment of Azoospermia with Sperm Retrieval and Intracytoplasmic Sperm Injection. (PDF, 66 KB) Human Reproduction, 1997. The relation between daily activities and scrotal temperature. Large polyps or multiple polyps can impact fertility by interfering with the ability of embryo to implant and should be removed.

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Microsurgery in Clinical Urology. (PDF, 5 MB) Urology, 1975. Radiation therapy: If this is aimed near the reproductive organs, it can increase the risk of fertility problems. A varicocele is like a varicose vein that can appear in the leg. 6,8,23 A high FSH level (10 to 20 mIU per mL [10 to 20 IU per L]) drawn on day 3 of the menstrual cycle is associated with infertility. The initial dosage of clomiphene is 50 mg daily for five days starting on day 3 to 5 of the menstrual cycle.