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Microsurgical Aspects of Varicocele. (PDF, 9 MB) Fertility and Sterility, 1979. Chromosomal defects Hereditary disorders, such as Klinefelter’s syndrome (when a male is born with two X chromosomes and one Y chromosome instead of one X and one Y) impacts the normal development of the male reproductive organs. The rising number of obese individuals may be due in part to an energy-rich diet as well as insufficient physical exercise.  In addition to other potential health risks, obesity can have a significant impact on male and female fertility. Radiation therapy: This can impair sperm production.

The pulsatile nature of GnRH is essential to normal gonadotropin release; a continuous stimulation inhibits their secretion. 33 Use of antioxidants such as zinc, vitamin E, or l-carnitine showed increased live birth rates in three small randomized controlled trials in couples undergoing assisted reproductive technology.

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If the sperm do not have the right shape, or they cannot travel rapidly and accurately towards the egg, conception may be difficult. Transsphenoidal resection of a microprolactinoma is 80-90% successful, but as many as 17% recur.

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The main approach to correcting or removing these uterine abnormalities is by hysteroscopy, a surgical method by which a narrow scope with a camera is placed within the uterine cavity. If necessary, they refer patients to a fertility clinic or local hospital for more specialized tests. By 2014, over 5 million people had been born after being conceived through IVF. Transrectal ultrasonography (TRUS) may reveal enlarged seminal vesicles, but this is not universal. Hofherr SE, Wiktor AE, Kipp BR, Dawson DB, Van Dyke DL. The Disappearing Y Chromosome – “I Told You So!” (PDF, 266 KB) Human Reproduction, 1997.

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It is better for a couple to see the doctor together. Tumors Cancers and nonmalignant tumors can affect the male reproductive organs directly, through the glands that release hormones related to reproduction, such as the pituitary gland, or through unknown causes. They are then processed and introduced to eggs by different methods. A blood test done on days 21 or 22 of a normal 28-day menstrual cycle can be used to test whether ovulation has occurred by measuring the progesterone level. When the eggs are mature, your doctor collects them with a device called a vaginal ultrasound probe. Retrograde Ejaculation: Is a condition in which semen is ejaculated into the bladder rather than out through the urethra because the bladder sphincter does not close during ejaculation.  If this disorder is present, ejaculate volume is small and urine may be cloudy after ejaculation.  This condition affects 1. 6,8 It is important for primary care physicians to be familiar with the workup and prognosis for infertile couples. Varicocele and male factor infertility treatment: a new meta-analysis and review of the role of varicocele repair. Opinion: Microsurgical TESE and the Distribution of Spermatogenesis in Non-obstructive Azoospermia. (PDF, 5 MB)Human Reproduction, 2000. Large submucosal uterine fibroids may make the uterus' cavity bigger, increasing the distance the sperm has to travel. Tubal catheterisation or cannulation: - With proximal tubal obstruction, selective salpingography plus tubal catheterisation, or hysteroscopic tubal cannulation, may be treatment options. Aetiology of Congenital Absence of Vas Deferens: Genetic Study of Three Generations. (PDF, 4 MB) Human Reproduction, 1993. When a man ejaculates and releases semen through the penis, the seminal fluid, or semen, helps transport the sperm toward the egg. Successful Pregnancy and Delivery after Calcium Ionophore Oocyte Activation in a Normozoospermic Patient with Previous Failed Fertilization after Intracytoplasmic Sperm Injection. (PDF, 57 KB) Fertility and Sterility, 2003. The severity usually depends on how near to the testicles the radiation was aimed.