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Investigations will be requested to prove the clinical diagnosis and to exclude other close possibilities. A couple should see a healthcare provider if they have not been able to become pregnant after 12 months of having sex regularly without birth control. Bhaskar Dutta/Photoshare Clinical definitions Infertility is “a disease of the reproductive system defined by the failure to achieve a clinical pregnancy after 12 months or more of regular unprotected sexual intercourse.”… (WHO-ICMART glossary1). “Infertility is the inability of a sexually active, non-contracepting couple to achieve pregnancy in one year. Once confirmed, the male partner is referred to a reproductive urologist, especially if the abnormality is severe. Estrogen causes negative feedback on the pituitary gland, inhibiting LH and FSH release. Embryos transfer is performed in the office under abdominal ultrasound guidance using a small, soft, sterile and flexible catheter.

A woman who keeps having miscarriages is also considered infertile. 8 Couples with unexplained infertility may want to consider another year of intercourse before moving to more costly and invasive therapies, such as assisted reproductive technology.

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Ejaculatory duct obstruction Complete and partial ejaculatory duct obstruction has been implicated as a cause of 1-5% of patients with male infertility. Surgical procedure to conserve the uterus for future pregnancy in patients suffering from massive adenomyosis.(PDF, 958 KB) Reproductive BioMedicine Online, 2010. Sex any other time, even the next day after ovulation, will not result in conception. “We generally advise couples to seek fertility evaluations if they are unable to conceive after 12 months of unprotected intercourse,” says Lawrence Ross, MD, president of the American Urological Association. Cantanucci and all of the nurses (especially Ashley).

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If oligospermia or azoospermia is noted, hypogonadism should be suspected. For patients wishing to conceive, the medical approach is not indicated, as it delays treatment for infertility.

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Germ cells (precursors to spermatozoa) are derived from the gonadal ridge and migrate to the testicle before testicular descent. Blockage of the ejaculatory duct: Sperm can be extracted directly from the testicles and injected into an egg in the laboratory. A prolactin level of more than 150 mcg/L suggests a pituitary adenoma, while levels greater than 300 mcg/L are nearly diagnostic. Infertility in women was ranked the 5th highest serious global disability5&6 (among populations under the age of 60). Quantitative Evaluation of Spermatogenesis by Testicular Histology in Men with Congenital Absence of the Vas Deferens Undergoing Epididymal Sperm Aspiration. (PDF, 3 MB) Human Reproduction, 1990. Transplantation of Rat Kidneys with Acute Tubular Necrosis into Salt-loaded and Normal Recipients. (PDF, 2 MB)Surgery, 1975. Unexplained infertility is not the same thing as having no explanation, but rather reflects the fact that the tests performed have been normal. This difference is not merely conceptual since the studies carried out in order to understand the causes and the treatment given in both cases are totally different. Mental stress: Stress can be a factor, especially if it leads to reduced sexual activity. Regression of Metastases after Nephrectomy for Renal Cell Carcinoma. (PDF, 1 MB) British Journal of Urology, 1975.


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See also
Infertility Hamster Test
Female Infertility Gene
Unexplained Infertility Possible to Get Pregnant