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Debate over whether health insurance companies (e.g. in the US) should be required to cover infertility treatment. Affected individuals displayed more severe forms of infertility such as azoospermia and severe oligozoospermia.[27] Other causes[edit] Factors that can cause male as well as female infertility are: DNA damage DNA damage reduces fertility in female ovocytes, as caused by smoking,[28] other xenobiotic DNA damaging agents (such as radiation or chemotherapy)[29] or accumulation of the oxidative DNA damage 8-hydroxy-deoxyguanosine[30] DNA damage reduces fertility in male sperm, as caused by oxidative DNA damage,[31] smoking,[28] other xenobiotic DNA damaging agents (such as drugs or chemotherapy)[32] or other DNA damaging agents including reactive oxygen species, fever or high testicular temperature.[33] The damaged DNA related to infertility manifests itself by the increased susceptibility to denaturation inducible by heat or acid [34] or by the presence of double-strand breaks that can be detected by the TUNEL assay.[35] General factors Diabetes mellitus,[36][37] thyroid disorders,[38] undiagnosed and untreated coeliac disease,[39][40][41][42] adrenal disease[43] Hypothalamic-pituitary factors Hyperprolactinemia Hypopituitarism The presence of anti-thyroid antibodies is associated with an increased risk of unexplained subfertility with an odds ratio of 1. In addition to a careful history, a physical evaluation may also be performed. From that point onwards, there is a progressive decline up to the point when a woman reaches 37 years of age. Treatment of Anovulatory Conditions Jump to section + Women with WHO group I ovulatory disorders should be counseled to achieve a normal body weight.

Article Sections Infertility is defined as the inability to achieve pregnancy after one year of regular, unprotected intercourse. Surgery for epididymal blockage: A blocked epididymis can be surgically repaired. Polycystic ovary syndrome (PCOS): The ovaries function abnormally and ovulation may not occur.

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Assessment of efficacy of varicocele repair for male subfertility: a systematic review. Fertility Evaluation: Obstetric and Gynecological History The obstetric and gynecological history should include: Reproductive history (children, mode of delivery, prematurity, stillbirth, extrauterine pregnancy, spontaneous and induced abortion, fertility and infertility in earlier relationships). Diagnosis Male infertility is usually diagnosed by a semen analysis. Ongoing Pregnancies and Birth after Intracytoplasmic Sperm Injection with Frozen-thawed Epididymal Spermatozoa. (PDF, 442 KB) Human Reproduction, 1995. GIFT (gamete intrafallopian tube transfer) and ZIFT (zygote intrafallopian transfer).  Like IVF, these procedures involve retrieving an egg, combining it with sperm in a lab, and then transferring it back to your body.

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The initial dosage of clomiphene is 50 mg daily for five days starting on day 3 to 5 of the menstrual cycle. Unexpected resilience of species with temperature-dependent sex determination at the Cretaceous–Palaeogene boundary. (PDF, 238 KB) Biology Letters, 2010. Primary infertility refers to cases in which no pregnancy has gone satisfactorily full term. It's used to remove polyps and fibroid tumors, divide scar tissue, and open up blocked tubes.

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It involves removing eggs from the ovary of a donor who has taken fertility drugs. Rarely, a blood clot may develop in an artery or vein, liver or kidney problems can arise, and respiratory distress may develop. Pro-life opposition to the destruction of embryos not transferred in vivo. Ovary Transplantation for Fertility Preservation in Cancer Patients: Fresh and Frozen. (PDF, 1 MB) Chapter 42 from textbook Clinial Infertility, 2010. Fertility treatments for women Fertility drugs might be prescribed to regulate or induce ovulation. Treatment of tubal obstruction generally requires referral for subspecialty care. Epidemiology[edit] Prevalence of infertility varies depending on the definition, i.e. on the time span involved in the failure to conceive. Infertility Tests History and physical examination – First and foremost, your fertility physician will take a very thorough medical and fertility history.