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Lead, toxic fumes and exposure to pesticides are suspected contributors to infertility. The couple should make sure to have sex during the three days before ovulation. Female factor Dysfunction of the female reproductive organs is also apparent in around 40% of infertile couples. Sperm were inserted into the oocyte (bar = 100 µm). (B) Marmoset blastocysts produced by ICSI. (bar = 100 µm).

Thankfully, even when the cause of infertility is not known, various fertility treatments can eventually lead to delivery of a healthy baby. Abundant Gene Conversion Between Arms of Palindromes in Human and Ape Y Chromosomes. (PDF, 340 KB)Nature, 2003.

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According to the literature survey, the most common causes of infertility are: male factor [5,7-9,13-15] such as sperm abnormalities [9,13,15], female factor [7-9,14-16] such as ovulation dysfunction [7,8] and tubal pathology [7-9], combined male and female factors [7,9,14,15] and unexplained infertility; where no obvious cause could be detected [7-9]. Records of one of the primary fertility awareness signs—basal body temperature—can detect ovulation by identifying the shift in temperature which takes place after ovulation. Therefore, pelvic ultrasonography is required before CC is initiated. [207] Pure FSH treatment for ovulation induction is another alternative for patients with PCOS who are clomiphene resistant. Aetiology of Congenital Absence of Vas Deferens: Genetic Study of Three Generations. (PDF, 4 MB) Human Reproduction, 1993.

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Therefore, data estimating the prevalence of infertility cited by various sources differs significantly.[8] A couple that tries unsuccessfully to have a child after a certain period of time (often a short period, but definitions vary) is sometimes said to be subfertile, meaning less fertile than a typical couple. Alcohol: Any amount of alcohol consumption can affect the chances of conceiving. Etiologies include cysts (midline and eccentric), ductal calcification and stones, postinfectious, and postoperative.

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Prevalence of Premature Ovarian Failure in Monozygotic and Dizygotic Twins. (PDF, 90 KB) Human Reproduction, 2007. Investigations Infertile couples are usually adviced to start their investigations after 12 months of trying to conceive or after 6 months if the female partner is more than 35 years old or immediately if there is an obvious cause for their infertility or subfertility [16]. Primary infertility refers to cases in which no pregnancy has gone satisfactorily full term. Infection: Some infections, such as gonorrhea or inflammation of the testicles, can affect sperm production or sperm health or can cause scarring that blocks the passage of sperm. 3) Insemination: Intrauterine insemination, also known as IUI, is a process by which sperm is washed and prepared for placement into the uterine cavity, therefore bypassing the cervix and bringing a higher concentration of motile sperm closer to the tubes and ovulated egg. Full history taking of both partners usually denotes the underlying problem [17-23], (Appendix 1). Because sperm generation time is just over two months, it is recommended to wait three months before repeat sampling. Therefore, data estimating the prevalence of infertility cited by various sources differs significantly.[8] A couple that tries unsuccessfully to have a child after a certain period of time (often a short period, but definitions vary) is sometimes said to be subfertile, meaning less fertile than a typical couple. This procedure is performed in the doctor’s office without anesthesia.