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Unexplained infertility[edit] In the US, up to 20% of infertile couples have unexplained infertility.[61] In these cases abnormalities are likely to be present but not detected by current methods. Ideally, using strict morphology criteria, a minimum of 5 – 15% normal forms leads to a better ability for sperm to fertilize the egg. This hormone then binds to another area of the brain called the pituitary gland and leads to the release of FSH (follicle stimulating hormone), a hormone that directly binds to cells in the ovary, leading to egg growth and maturation. Rarely, a blood clot may develop in an artery or vein, liver or kidney problems can arise, and respiratory distress may develop. Diagnostic evaluation of the infertile female: a committee opinion. This can reveal signs of endometriosis, scarring, blockages, and some irregularities of the uterus and fallopian tubes.

22 Treatment of Male Infertility Jump to section + Underlying etiology determines the therapeutic course, although male infertility is unexplained in 40% to 50% of cases. Hypospadias: The urethral opening is under the penis, instead of its tip.

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Additionally, transvaginal ultrasound affords the opportunity for your physician to assess the relative number of available eggs. Female infertility has many possible causes, such as irregular ovulation, uterine fibroids, fallopian tube blockage, PCOS, or endometriosis. Clark AM, Thornley B, Tomlinson L, Galletley C, Norman RJ.

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London, United Kingdom: National Institute for Health and Clinical Excellence (NICE); February 2013:1–63. (Clinical guideline no. Pregnancies after Testicular Sperm Extraction and Intracytoplasmic Sperm Injection in Non-obstructive Azoospermia. (PDF, 3 MB) Human Reproduction, 1995.

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No Differences in Outcome after Intracytoplasmic Sperm Injection with Fresh or with Frozen-thawed Epididymal Spermatozoa. (PDF, 66 KB) Human Reproduction, 1999. Fertilizing Capacity of Epididymal and Testicular Sperm with ICSI. (PDF, 5 MB) Frontiers in Endocrinology, 1995. Your doctor may ask you many of the following questions: How long have you been trying to get pregnant? Possible problems could be that the egg is not released at the optimum time for fertilization, that it may not enter the fallopian tube, sperm may not be able to reach the egg, fertilization may fail to occur, transport of the zygote may be disturbed, or implantation fails. Ovulation induction and intrauterine insemination are used after completion of the treatment in hopes of expediting the establishment of a pregnancy before relapse of the disease. [39, 157, 158] Treatment of Ovarian Factors Ovulation induction is the appropriate treatment for infertile patients who have dysfunction of the hypothalamic-pituitary-ovarian axis. The epididymis is a coil-like structure in the testicles which helps store and transport sperm. Insulin-sensitising drugs (metformin, rosiglitazone, pioglitazone, D-chiro-inositol) for women with polycystic ovary syndrome, oligo amenorrhoea and subfertility.