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Chemotherapy: Some chemotherapy drugs can result in ovarian failure. Intracytoplasmic Sperm Injection. (PDF, 4 MB) Chapter 47 from textbook Current Therapy in Equine Reproduction, 2006. If he has two X chromosomes and one Y chromosome, as in Klinefelter's syndrome, the testicles will develop abnormally and there will be low testosterone and a low sperm count or no sperm. Mannitol Induced Central Nervous System Toxicity in Renal Failure. (PDF, 4 MB) Investigative Urology, 1972.

Treatment of the cause: 28. Tubal and uterine factors: 4. Anovulation can also cause cessation of periods (secondary amenorrhea) or excessive bleeding (dysfunctional uterine bleeding). Further investigations may be requested according to the clinical presentation and the results of preliminary tests. It’s common for couples to experience issues with infertility. Diverse Spermatogenic Defects in Humans Caused by Y Chromosome Deletions Encompassing a Novel RNA-binding Protein Gene. (PDF, 7 MB) Nature Genetics, 1995.

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Tubal catheterisation or cannulation: - With proximal tubal obstruction, selective salpingography plus tubal catheterisation, or hysteroscopic tubal cannulation, may be treatment options. Tests and trials are available, but testing does not always reveal a specific cause. The male partner can be evaluated for infertility or subfertility using a variety of clinical interventions, and also from a laboratory evaluation of semen.” (Semen manual, 5th Edition3). Females[edit] The following causes of infertility may only be found in females.

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But for other men, advances in male infertility treatment offer real help. If a semen analysis is found to be abnormal, generally it is first repeated to confirm the abnormality.

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Gerrits T, Shaw M (2010). "Biomedical infertility care in sub-Saharan Africa: a social science review of current practices, experiences and view points". Bhaskar Dutta/Photoshare Clinical definitions Infertility is “a disease of the reproductive system defined by the failure to achieve a clinical pregnancy after 12 months or more of regular unprotected sexual intercourse.”… (WHO-ICMART glossary1). “Infertility is the inability of a sexually active, non-contracepting couple to achieve pregnancy in one year. Illegal drugs: Some women who use marijuana or cocaine may have fertility problems. Sulfasalazine: This anti-inflammatory drug can significantly lower a man's sperm count. Painful or heavy periods Most women experience cramps with their periods. They are usually young patients with a history of polycystic ovarian syndrome or oligo-ovulation who responded with elevated E2 levels (3000 pc/mL) and multiple follicles (>15) and patients in whom the ovulation has been triggered by the administration of exogenous hCG. [196, 197] Ovarian hyperstimulation syndrome usually has 2 phases. Both infertility and subfertility are defined as the inability to conceive after a certain period of time (the length of which vary), so often the two terms overlap. Other considerations include preconception screening and vaccination for preventable diseases such as rubella and varicella, sexually transmitted infections, and cervical cancer, based on appropriate guidelines and risk. Orchitis The most common cause of acquired testicular failure in adults is viral orchitis, such as that caused by the mumps virus, echovirus, or group B arbovirus. Prevalence of Premature Ovarian Failure in Monozygotic and Dizygotic Twins. (PDF, 90 KB) Human Reproduction, 2007. This diagnosis is therefore shared by 15% of couples attempting to conceive.