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Human menopausal gonadotropin, or hMG (Repronex): This contains both FSH and LH. 29 When the semen analysis is abnormal, referral to a male fertility specialist or reproductive endocrinologist is warranted. Demographic definitions of infertility An inability of those of reproductive age (15-49 years) to become or remain pregnant within five years of exposure to pregnancy. (DHS2) An inability to become pregnant with a live birth, within five years of exposure based upon a consistent union status, lack of contraceptive use, non-lactating and maintaining a desire for a child. (Trends in prevalence4). 8 Couples with unexplained infertility may want to consider another year of intercourse before moving to more costly and invasive therapies, such as assisted reproductive technology.

Septate uterus The hypothesis that a uterine septum can cause infertility is controversial. When this is not the case, a couple facing male infertility may turn to a sperm donor or adoption to help build their family.

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Human male infertility, the Y chromosome, and dinosaur extinction. (PDF, 1 MB) Middle East Fertility Society Journal, January 18, 2011.Fertility Articles – PDF Archive | Infertility Center If you have any questions, you may call us at  (314) 576-1400. Surgical therapy of a macroprolactinoma is rarely curative, although this should be considered in patients with visual-field defects or those who do not tolerate bromocriptine. 1,2 However, if your partner is 35 years old or over, you or your partner may be considered infertile if you haven’t conceived after 6 months of unprotected sex. Results of Microsurgical Vasoepididymostomy: Role of Epididymis in Sperm Maturation. (PDF, 3 MB) Human Reproduction, 1989. The Male-specific Region of the Human Y Chromsome is a Mosaic of Discrete Sequence Classes. (PDF, 754 KB) Nature, 2003. If necessary, they refer patients to a fertility clinic or local hospital for more specialized tests.

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Infertility may be caused by blockage of the Fallopian tube due to malformations, infections such as chlamydia or scar tissue. Low weight: Obesity is not the only way in which weight can impact fertility.

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Epidemiology[edit] Prevalence of infertility varies depending on the definition, i.e. on the time span involved in the failure to conceive. About 10% of reproductive age women are affected by endometriosis. 1 Among couples 15 to 44 years of age, nearly 7 million have used infertility services at some point. These include advancing maternal age, severe male factor infertility (whereby ICSI can be used to fertilize the egg), and endometriosis, amongst many others. We recommend immediate evaluation for a couple attempting pregnancy when the woman has a prior history of pelvic infection. Metformin (Glucophage) is another type of medication that may help you ovulate normally if you have insulin resistance or PCOS (polycystic ovarian syndrome). Diet: A lack of folic acid, iron, zinc, and vitamin B-12 can affect fertility. Having an irregular cycle, including missing periods, can contribute to infertility, as it means a woman may not be regularly ovulating. As treatment begins, couples may experience cycles of optimism and despair with each passing menstrual cycle. Hypogonadotropic Hypopituitarism: Low pituitary gland output of LH and FSH.  This condition arrests sperm development and causes the progressive loss of germ cells from the testes and causes the seminiferous tubules and Leydig (testosterone producing) cells to deteriorate.  May be treated with the drug Serophene.  However, if all germ cells are destroyed before treatment commences, the male may be permanently infertile. However, about one in five cases of infertility has no clear diagnosed cause.[73] In Britain, male factor infertility accounts for 25% of infertile couples, while 25% remain unexplained. Compensatory and Obligatory Renal Growth in Rats. (PDF, 1 MB) American Journal of Physiology, 1974.