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Intrauterine insemination. For this procedure, after semen gets rinsed with a special solution, a doctor places it into your uterus when you're ovulating. Intravenous fluids (ie, isotonic sodium chloride solution) must be administered until hemodilution is achieved.

Author disclosure: No relevant financial affiliations. WHO Manual for the Standardized Investigation and Diagnosis of the Infertile Couple. Microsurgery and Andrology. (PDF, 5 MB) Chapter from textbook, 1991. 8 Couples with unexplained infertility may want to consider another year of intercourse before moving to more costly and invasive therapies, such as assisted reproductive technology.

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Infertility might contribute to stress, anxiety, and depression in couples trying to conceive, and treatment can be medically invasive and expensive. Metformin (Glucophage): If Clomifene is not effective, metformin may help women with PCOS, especially when linked to insulin resistance.

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Only active, undamaged sperm are chosen for injections. Men should undergo evaluation with a semen analysis. Done as part of an IVF treatment, ICSI involves injecting a single sperm into an egg. Unlike IVF, in which actual fertilization is observed and confirmed in the laboratory, GIFT does not allow visual confirmation of fertilization. Infertility in Men Below you will find a list of some of the most common causes of infertility in men.

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Idiopathic Hypercalciuria. (PDF, 1 MB) New England Journal of Medicine, 1971. Outlook For couples who experience fertility problems and those who wish to have children at an older age, there are more options available than ever before. Cystic fibrosis: This is a chronic disease that results in the creation of a sticky mucus. If a tube is blocked and filled with fluid (called a hydrosalpinx), then minimally invasive surgery (laparoscopy or hysteroscopy) to either remove the tube or block/separate it from the uterus prior to any fertility treatments is recommended. Once the follicles (fluid filled sacs containing the eggs) reach a mature size, an HCG injection is administered which leads to final development and maturation of the eggs. In 1985, he constructed the pelvi-trainer = laparo-trainer, a practical surgical model whereby colleagues could practice laparoscopic techniques. The Three-kidney Rat Model. (PDF, 2 MB) Investigative Urology, 1974. Hypogonadotropic Hypopituitarism: Low pituitary gland output of LH and FSH.  This condition arrests sperm development and causes the progressive loss of germ cells from the testes and causes the seminiferous tubules and Leydig (testosterone producing) cells to deteriorate.  May be treated with the drug Serophene.  However, if all germ cells are destroyed before treatment commences, the male may be permanently infertile. Less common factors The following other factors may also be responsible for infertility in a smaller proportion of cases: • Genetic abnormalities within eggs, sperm or both • An abnormal uterine cavity, including the presence of fibroids or polyps • Immunological infertility, whereby either the male or female partner produces anti-bodies against sperm cells or implantation of an embryo • Abnormal cervical mucus which hinders the passage of sperm to the uterus and fallopian tubes Unexplained infertility Even when investigations have been extensive, some couples will have no reason with which to explain their infertility. Antibodies against the sperm in the cervical mucus particularly often occur in sterile marriages.