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In many cases, there are tests that can help find the cause(s) of male infertility. Unfortunately, some men have to cope with the reality that nothing can be done about their infertility.

Management of the infertile couple: an evidence-based protocol. If a woman has an ovulation disorder, she may ovulate infrequently or not all. They include: Clomifene (Clomid, Serophene): This encourages ovulation in those who ovulate either irregularly or not at all, because of PCOS or another disorder. In some cases, the cause of infertility or subfertility could not be suspected from the history taking and clinical examination. It stimulates the ovaries to mature egg follicles. A review of systems and physical examination of the endocrine and gynecologic systems should be performed.

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Pretesticular causes of infertility Pretesticular causes of infertility include congenital or acquired diseases of the hypothalamus, pituitary, or peripheral organs that alter the hypothalamic-pituitary axis. If an endocrinopathy, such as hyperprolactinemia, is diagnosed, the underlying cause should be treated.

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Although 60% of patients have evidence of antisperm antibodies after vasectomy, the clinical significance has not been completely elucidated. Young syndrome is a condition that leads to inspissation of material and subsequent blockage of the epididymis. Isodicentric Y Chromosomes and Sex Disorders as Byproducts of Homologous Recombination that Maintains Palindromes. (PDF, 1 MB) Cell, 2009. It can either be used to inspect and diagnose certain conditions or to surgically correct an abnormality such as removing scar tissue, endometriosis, or a damaged fallopian tube. In-vitro fertilization and donor insemination are major procedures involved. Illegal drugs: Consumption of marijuana and cocaine can lower the sperm count.

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Epidemiology[edit] Prevalence of infertility varies depending on the definition, i.e. on the time span involved in the failure to conceive. What Forms of Male Infertility are there left to Cure? (PDF, 2 MB) Human Reproduction, 1995. Treatment[edit] Treatment depends on the cause of infertility, but may include counselling, fertility treatments, which include in vitro fertilization. Testicular neoplasia, commonly producing estrogen, usually causes infertility. However, a survey has suggested that the 3 days most likely to offer a fertile window are the 2 days before ovulation plus the 1 day of ovulation. Insulin-sensitising drugs (metformin, rosiglitazone, pioglitazone, D-chiro-inositol) for women with polycystic ovary syndrome, oligo amenorrhoea and subfertility. No role for: Post-coital testing for cervical mucous. Endometrial Biopsy. The resulting embryos are then transferred into the uterus of the future mother, known as the recipient. Although 60% of patients have evidence of antisperm antibodies after vasectomy, the clinical significance has not been completely elucidated. A defect in any of these sperm structures may result in infertility that will not be detected by semen analysis.[60] Antisperm antibodies cause immune infertility.[23][24] Cystic fibrosis can lead to infertility in men. In cases when the quality of sperm is very poor, or sperm is completely absent in the ejaculate (azoospermia), donor’s sperm can be used (if culturally acceptable).