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Outcome of Intracytoplasmic Sperm Injection with Testicular Spermatozoa in Obstructive and Non-obstructive Azoospermia. (PDF, 426 KB) Human Reproduction, 1996. The results of these tests help determine the best fertility treatment.

Exposure to toxic agents can occur from occupational hazards or contaminated air, water, food supply or other exposures. Ovulation often can be detected by keeping a menstrual calendar or using an ovulation predictor kit. Other conditions Various other lesions and diseases, such as CNS tumors, temporal lobe seizures, and many drugs (eg, dopamine antagonists) may interrupt the hypothalamic-pituitary axis at the hypothalamus. Outcome of Intracytoplasmic Sperm Injection with Testicular Spermatozoa in Obstructive and Non-obstructive Azoospermia. (PDF, 426 KB) Human Reproduction, 1996.

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Donor semen should be free from any STI-producing organisms, including HIV. Obesity and increased risk for oligozoospermia and azoospermia. Congenital Absence of the Vas Deferens: The Fertilizing Capacity of Human Epididymal Sperm. (PDF, 3 MB) New England Journal of Medicine, 1990. Some facts about conception and fertility A doctor can give advice and carry out some preliminary assessments. Also, polymorphisms in folate pathway genes could be one reason for fertility complications in some women with unexplained infertility.[62] However, a growing body of evidence suggests that epigenetic modifications in sperm may be partially responsible.[63][64] Diagnosis[edit] If both partners are young and healthy and have been trying to conceive for one year without success, a visit to a physician or women's health nurse practitioner (WHNP) could help to highlight potential medical problems earlier rather than later.

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But anything within a few days of that can be considered normal, as long as those cycles are consistent. Pregnancy after Vasovasostomy for Vasectomy Reversal: A Study of Factors Followed for 10 Years. (PDF, 3 MB)Human Reproduction, 1989. In fact, endometriosis accounts for roughly 20 to 40 percent of women’s infertility issues.  Pain during sex: Painful sex for women is so normalized that many think it’s just a part of life. Infertility in men Semen and sperm The most common cause of infertility in men is poor-quality semen, the fluid containing sperm that's ejaculated during sex. A treatment plan should be generated according to the diagnosis, duration of infertility, and the woman's age.

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A Physical Map of the Human Y Chromosome. (PDF, 160 KB) Nature, 2001. Inhibin B levels have been reported to decrease with increasing weight, which results in decreased Sertoli cells and sperm production. Risk factors for the formation of antisperm antibodies in men include the breakdown of the blood‑testis barrier, trauma and surgery, orchitis, varicocele, infections, prostatitis, testicular cancer, failure of immunosuppression and unprotected receptive anal or oral sex with men.[23][24] Sexually transmitted infections[edit] Infections with the following sexually transmitted pathogens have a negative effect on fertility: Chlamydia trachomatis and Neisseria gonorrhoeae. In a third of cases, the reason lies only with the man; in another third, it is because of the woman; and in the rest of the cases, it is a combination of both, or the cause is unknown. Studies on Testicular Biopsies from Vasectomized Men. (PDF, 18 MB) Chapter 21 from Vasectomy: Immunologic and Pathophysiologic Effects in Animals and Man, 1979. They can also carry out some basic tests on both partners to see if there is an identifiable reason for not having achieved a pregnancy. This may reflect an unknown immunological incompatibility or other unknown problem with fertilization or implantation. Studies have shown that approximately 70% of miscarriages are due to chromosomal abnormalities. Medication. If you have ovulation problems, you may be prescribed drugs such as clomiphene citrate (Clomid, Serophene), gonadotropins (such as Gonal-F, Follistim, Humegon and Pregnyl), or letrozole.