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Cervical factors are also thought to play a minor role, although they are rarely the sole cause. Calcification of the Seminal Vesicles and Vas Deferens in a Uremic Patient. (PDF, 3 MB) The Journal of Urology, 1971. 6,23 Anovulatory women should have further investigation to determine treatable causes such as thyroid disorders or hyperprolactinemia based on symptoms. Additionally, surgery, radiation or chemotherapy to treat tumors can affect male fertility. Several studies indicate that in some cases, a simple change in lifestyle could help patients suffering from anovulation.

As the major causes of infertility are sperm abnormalities, ovulation dysfunction, and fallopian tube obstruction, the preliminary adviced investigations for the infertile couple should be focused on semen analysis (to be compared with the WHO reference values [27]), detection of ovarian function by hormonal assay (early follicular FSH and LH levels, and mid-luteal progesterone), and evaluation of tubal patency by hysterosalpingography (HSG) [17-32], (Appendix 3). GIFT (gamete intrafallopian tube transfer) and ZIFT (zygote intrafallopian transfer).  Like IVF, these procedures involve retrieving an egg, combining it with sperm in a lab, and then transferring it back to your body. It is increasingly recognized that egg quality is of critical importance and women of advanced maternal age have eggs of reduced capacity for normal and successful fertilization. Abnormal sperm: The sperm may have an unusual shape, making it harder to move and fertilize an egg. It usually involves treatment implication counselling, emotional support counselling, and therapeutic counselling [38,39].

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Afterward, the embryos are incubated again and then transferred to the cavum uteri of the woman. This abnormality is usually surgically corrected in infancy.

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In such circumstances, it is recommended not to prescribe any medication until all basic investigations are done and its results received. Graft-versus-host Reactivity and Renal Allograft Survival in Rats Given Allogeneic Spleen Cells or Spleen Allografts.(PDF, 2 MB) Transplantation, 1976. There are three main types of fertility treatment: medical treatment (such as ovulation induction therapy); surgical treatment (such as laparoscopy and hysteroscopy); and the different assisted reproduction techniques [37]. Even with the testis shielded, radiation therapy below the diaphragm may lead to infertility due to the release of reactive oxygen free radicals. Obese women have a higher rate of recurrent, early miscarriage compared to non-obese women. For a woman to conceive, certain things have to happen: vaginal intercourse must take place around the time when an egg is released from her ovary; the system that produces eggs has to be working at optimum levels; and her hormones must be balanced.[54] For women, problems with fertilisation arise mainly from either structural problems in the Fallopian tube or uterus or problems releasing eggs.

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Endometriosis may be treated through laparoscopic surgery. Common causes of infertility of females include: ovulation problems (e.g. polycystic ovarian syndrome, PCOS, the leading reason why women present to fertility clinics due to anovulatory infertility.[58]) tubal blockage pelvic inflammatory disease caused by infections like tuberculosis age-related factors uterine problems previous tubal ligation endometriosis advanced maternal age immune infertility Males[edit] The main cause of male infertility is low semen quality. Understanding what defines normal fertility is crucial to helping a person, or couple, know when it is time to seek help. Sometimes there may be simple ways to make lifestyle adjustments to improve fertility, while other underlying causes may require treatment. The resulting sperm count (also called spermiogram) allows identifying various pathologies. Some suggest that the number of times a couple has intercourse should be reduced to increase sperm supply, but this is unlikely to make a difference.