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In some cases, the reproductive urologist can improve semen function by recommending certain lifestyle changes, by hormonal treatments, or by surgery. If ovulation does not occur with the 50-mg dose, the CC dose must be increased in subsequent cycles to 100 mg for 5 days. A woman of reproductive age who is using artificial insemination to conceive (with either partner or donor sperm) after 6 failed trials. Consider earlier referral to infertility specialists where: - the woman is aged 36 years or over. - there is a known clinical cause of infertility or a history of predisposing factors for infertility. - treatment is planned that may result in infertility (such as treatment for cancer). - People who are concerned about their fertility and who are known to have chronic viral infections such as hepatitis B, hepatitis C or HIV. Other factors that can affect a woman's chances of conceiving include being overweight or underweight,[56] or her age as female fertility declines after the age of 30.[57] Sometimes it can be a combination of factors, and sometimes a clear cause is never established. A Modern View of Male Infertility. (PDF, 7 MB) From The Infertile Male: Advanced Assisted Reproductive Technology, 1994. Factors affecting Fertility Caffeinated beverages: - No evidence on effect of caffeine on fertility. Alcohol - Female patients should be informed that 1 or 2 units of alcohol once or twice per week reduces risk of harming a developing fetus. - Intoxication may affect semen quality.

The pulsatile nature of GnRH is essential to normal gonadotropin release; a continuous stimulation inhibits their secretion. The sperm is washed in a fluid and the best specimens are selected.

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Other factors that can affect a woman's chances of conceiving include being overweight or underweight,[56] or her age as female fertility declines after the age of 30.[57] Sometimes it can be a combination of factors, and sometimes a clear cause is never established. At least one open tube is required for IUI, and any sperm abnormality cannot be severe, otherwise the sperm will not be able to swim to and fertilize the egg. Problems maintaining erection A man’s ability to maintain an erection is often linked to his hormone levels. Inhibin B levels have been reported to decrease with increasing weight, which results in decreased Sertoli cells and sperm production. Endometriosis Endometriosis is when the tissue of the uterine lining grows outside of the uterus. The use of CC is contraindicated in cases of ovarian cyst, pregnancy, and liver disease.

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Environmental vs Genetic Sex Determination: A Possible Factor in Dinosaur Extinction? (PDF, 307 KB) Fertility and Sterility, 2004. Endometriosis may be treated through laparoscopic surgery. With this treatment, the patient experience spermatogenesis, and therefore, it has the chance to have offspring if he wants to. Exposure to some chemicals: Some pesticides, herbicides, metals, such as lead, and solvents have been linked to fertility problems in both men and women. Chronic anovulation is a common cause of infertility. Sperm Granuloma and Reversibility of Vasectomy. (PDF, 11 MB) Lancet, 1977.

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Environmental vs Genetic Sex Determination: A Possible Factor in Dinosaur Extinction? (PDF, 307 KB) Fertility and Sterility, 2004. Each day of abstinence is typically associated with an increase in semen volume of 0. Acquired anestrus may result from previous oophorectomy, exogenous hormonal treatment (including glucocorticoids), profound hypothyroidism, or ovarian disease (cysts or neoplasia). However, nowadays, spermatozoa can be extracted by means of a testicular puncture. Klinefelter�s Syndrome: Is a genetic condition in which each cell in the human body has an additional X chromosome--men with Klinefelter�s Syndrome have one Y and two X chromosomes.  Physical symptoms include peanut-sized testicles and enlarged breasts.  A chromosome analysis is used to confirm this analysis.  If this condition is treated in its early stages (with the drug hCG), sperm production may commence and/or improve.  However, Klinefelter�s Syndrome eventually causes all active testicular structures to atrophy.  Once testicular failure has occurred, improving fertility is impossible. A specimen is collected by masturbation into a clean, dry, sterile container or during coitus using special condoms (containing no spermicidal lubricants). Ovarian Transplantation between Monozygotic Twins Discordant for Premature Ovarian Failure. (PDF, 315 KB) The New England Journal of Medicine, 2005. Perspectives on infertility consultations in primary care: a qualitative study. Showell MG, Brown J, Yazdani A, Stankiewicz MT, Hart RJ. Diet: A lack of folic acid, iron, zinc, and vitamin B-12 can affect fertility. Afterward, the mucus specimen is phase-microscopically examined.