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Ovarian Transplantation in a Series of Monozygotic Twins Discordant for Ovarian Failure. (PDF, 188 KB) The New England Journal of Medicine, 2007. WHO categorizes ovulatory disorders into three groups: group I is caused by hypothalamic pituitary failure (10%), group II results from dysfunction of hypothalamic-pituitary-ovarian axis (85%), and group III is caused by ovarian failure (5%). Testosterone is converted to dihydrotestosterone (DHT) by the action of 5-alpha reductase, both locally and in the periphery, and to estrogen in the periphery.

Understanding what’s causing your fertility difficulties can help you find out what treatment is right for you and your partner.Fertility What is Normal Fertility and When Does it Become Infertility? Women with anovulation may be treated in the primary care setting with clomiphene to induce ovulation. This means it’s more difficult to become pregnant and the chance of miscarriage is higher.  Unexplained infertility  Sometimes, doctors are unable to find the reason for infertility, despite running the required fertility tests. The mammary glands are also controlled by the pituitary gland, so lactation can also be affected. A Modern View of Male Infertility. (PDF, 7 MB) From The Infertile Male: Advanced Assisted Reproductive Technology, 1994.

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Microsurgery for Vasectomy Reversal and Vasoepididymostomy. (PDF, 13 MB) Urology, 1984. These include: non-steroidal anti-inflammatory drugs (NSAIDs) – long-term use or a high dosage of NSAIDs, such as ibuprofen or aspirin, can make it more difficult to conceive chemotherapy – medicines used for chemotherapy can sometimes cause ovarian failure, which means your ovaries will no longer be able to function properly neuroleptic medicines – antipsychotic medicines often used to treat psychosis; they can sometimes cause missed periods or infertility spironolactone – a type of medicine used to treat fluid retention (oedema); fertility should recover around 2 months after you stop taking spironolactone Illegal drugs, such as marijuana and cocaine, can seriously affect fertility and make ovulation more difficult. Causes of Sterility in Men Image: “Colorized sperm sample under the light microscope” by Bobjgalindo. This combination of laboratory test results may indicate ovarian insufficiency or diminished ovarian reserve.

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Some respond by actively avoiding the issue altogether; middle-class men are the most likely to respond in this way.[21] In the United States some treatments for infertility, including diagnostic tests, surgery and therapy for depression, can qualify one for Family and Medical Leave Act leave. The most commonly prescribed injections that stimulate the ovary are called gonadotropins. This technique involves an injection of a single healthy sperm directly injected into mature egg.

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IUI is more commonly done when the man has a low sperm count, decreased sperm motility, or when infertility does not have an identifiable cause. They can include: Changes in hair growth Changes in sexual desire Pain, lump, or swelling in the testicles Problems with erections and ejaculation Small, firm testicles   When to See the Doctor If you are under 35 and have been trying to get pregnant without success for a year, see your doctor. The sperm must provide the zygote with DNA, centrioles, and activation factor for the embryo to develop. ARTICLES FROM THE 1990s Microsurgery, Andrology, and Its Role in IVF. (PDF, 6 MB) Chapter in text book, Advances in Assisted Reproductive Technology, 1990. Human menopausal gonadotropin, or hMG (Repronex): This contains both FSH and LH. To Transplant or Not to Transplant – That Is the Question. (PDF, 3 MB) 2010.