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The pregnancy rate fluctuates from 20-35%, and the expected ectopic pregnancy rate is as high as 20%. 3  Sometimes, a couple who’ve already had a child can have trouble conceiving again. However, the optimal dosage and length of administration is under investigation. [170, 171] Aromatase inhibitors are generally well tolerated. 6,8 It is important for primary care physicians to be familiar with the workup and prognosis for infertile couples. Are Sequence Family Variants Useful for Identifying Deletions in the Human Y Chromosome? (PDF, 377 KB) The American Journal of Human Genetics, 2004.

Sex any other time, even the next day after ovulation, will not result in conception. “We generally advise couples to seek fertility evaluations if they are unable to conceive after 12 months of unprotected intercourse,” says Lawrence Ross, MD, president of the American Urological Association. Risk factors for the formation of antisperm antibodies in men include the breakdown of the blood‑testis barrier, trauma and surgery, orchitis, varicocele, infections, prostatitis, testicular cancer, failure of immunosuppression and unprotected receptive anal or oral sex with men.[23][24] Sexually transmitted infections[edit] Infections with the following sexually transmitted pathogens have a negative effect on fertility: Chlamydia trachomatis and Neisseria gonorrhoeae. Females[edit] The following causes of infertility may only be found in females. Possible reasons for abnormal semen include: a lack of sperm – you may have a very low sperm count or no sperm at all sperm that aren't moving properly – this will make it harder for sperm to swim to the egg abnormal sperm – sperm can sometimes be an abnormal shape, making it harder for them to move and fertilise an egg Many cases of abnormal semen are unexplained.

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Basal body temperatures are no longer considered a reliable indicator of ovulation, and are not recommended for evaluating ovulation. It is important to undergo a thorough fertility evaluation to determine the problem. Unicornuate uterus is associated with renal abnormalities including absence of a kidney or presence of a pelvic kidney; this occurs in 15% of cases.

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Microsurgery for the Undescended Testicle. (PDF, 5 MB) Urologic Clinics of North America, 1982. A Modern View of Male Infertility. (PDF, 7 MB) From The Infertile Male: Advanced Assisted Reproductive Technology, 1994.

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Assisted Reproductive Technology: Using Ejaculated, Fresh, and Frozen-thawed Epididymal and Testicular Spermatozoa Gives Rise to Comparable Results after Intracytoplasmic Sperm Injection. (PDF, 5 MB) Fertility and Sterility, 1995. However, a survey has suggested that the 3 days most likely to offer a fertile window are the 2 days before ovulation plus the 1 day of ovulation. Online support from organizations such as Resolve can be helpful. High-cost treatments are out of financial reach for some couples. High-cost treatments are out of financial reach for some couples. The likelihood of fertilization improves significantly for men with low sperm concentrations. These microdeletions are not observed on regular karyotype testing; rather, their identification requires polymerase chain reaction (PCR)–based sequence-tagged site mapping or Southern blot analysis.